Imaging of Brain Perfusion
Brain perfusion by SPECT or PET is a well-established and reliable method to measure regional cerebral blood flow (rCBF). The normal adult brain perfusion is symmetrical with higher tracer distribution in the temporal, parietal and occipital (visual) cortices, basal ganglia, thalami and cingulate gyrus than in the white matter and interhemispheric fissure . Depending whether the eyes are open or closed, an increase of ca. 30 % more in the occipital visual cortex can be observed . Motor and sensory stimuli can have asymmetrical effects. In the newborn, perfusion is slightly lowered in the frontal and temporoparietal regions and reaches an “adult” pattern within the first 2 years of life . As the same SPECT pattern may be encountered in several pathologies (Table 1), detailed knowledge of the patient’s symptoms and the functional area of the brain likely to be involved is important.
KeywordsTraumatic Brain Injury Attention Deficit Hyperactivity Disorder Chronic Fatigue Syndrome Brain Perfusion Chronic Traumatic Encephalopathy
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