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Application of Green Metrics Analysis to the Synthesis of Dicyclohexylcarbodiimide (DCC) – Comparison of Chlorine Versus Non-chlorine-Based Routes

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Chemistry Beyond Chlorine

Abstract

Green metrics at four levels of analysis are determined for various synthesis plans for dicyclohexylcarbodiimide (DCC) covering material efficiency, environmental impact, safety-hazard impact, and energy input demands to identify the greenest plan available to make this important dehydrating reagent. Chlorine-based routes using phosgene chemistry are juxtaposed against non-chlorine-based routes.

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Author information

Authors and Affiliations

  1. CareerChem, 504-1129 Don Mills Road, Toronto, ON, M3B 2W4, Canada

    John Andraos

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  1. John Andraos
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Correspondence to John Andraos .

Editor information

Editors and Affiliations

  1. Ca' Foscari University of Venice Environmental Sciences, Venice, Italy

    Pietro Tundo

  2. Institute of Elemento-Organic Chemistry, Nankai University Institute of Elemento-Organic Chemistry, Tianjin, China

    Liang-Nian He

  3. Chemistry Department, Lomonosov Moscow State University Chemistry Department, Moscow, Russia

    Ekaterina Lokteva

  4. Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro-RJ, Brazil

    Claudio Mota

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Andraos, J. (2016). Application of Green Metrics Analysis to the Synthesis of Dicyclohexylcarbodiimide (DCC) – Comparison of Chlorine Versus Non-chlorine-Based Routes. In: Tundo, P., He, LN., Lokteva, E., Mota, C. (eds) Chemistry Beyond Chlorine. Springer, Cham. https://doi.org/10.1007/978-3-319-30073-3_22

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