Carrier-Mediated Transport

  • Jürgen RettingerEmail author
  • Silvia Schwarz
  • Wolfgang Schwarz


The chapter on Carrier-Mediated Transport presents characteristics of carriers compared to channels and how electrophysiological methods can be used for functional characterization. For illustration three examples are presented: the anion exchanger of red blood cells, the ubiquitous Na+,K+-ATPase and the neuronal neurotransmitter transporter for GABA.

“The anion exchanger is an example for an electrically silent transporter that, nevertheless, can be investigated by electrophysiology. The Na+,K+-ATPase and the GABA transporter are examples for a primarily and a secondarily active transporter, respectively. “

These examples are also used to discuss channel-like characteristics of carriers.


Anion Exchanger Voltage Dependence Access Channel Gaba Transporter Neurotransmitter Transporter 
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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Jürgen Rettinger
    • 1
    Email author
  • Silvia Schwarz
    • 2
  • Wolfgang Schwarz
    • 3
  1. 1.Multi Channel Systems GmbHReutlingenGermany
  2. 2.Shanghai Research Center for Acupuncture and Meridians, Shanghai Key Laboratory for Acupuncture Mechanism and Acupoint FunctionFudan UniversityShanghai-PudongChina
  3. 3.Institut für BiophysikGoethe-Universität FrankfurtFrankfurt am MainGermany

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