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Diagnosis and Management of Hereditary Meningioma and Vestibular Schwannoma

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Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 205)

Abstract

Bilateral vestibular schwannomata and meningiomata are the tumours most commonly associated with neurofibromatosis type II (NF2). These tumours may also be seen in patients with schwannomatosis and familial meningioma, but these phenotypes are usually easy to distinguish. The main diagnostic challenge when managing these tumours is distinguishing between sporadic disease which carries low risk of subsequent tumours or NF2 with its associated morbidities and reduced life expectancy. This chapter outlines some of the diagnostic and management considerations along with associated evidence.

Keywords

Vestibular schwannoma Meningioma Neurofibromatosis type II NF2 Schwannomatosis 

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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Department of Clinical GeneticsGuy’s and St Thomas’ NHS Foundation TrustLondonUK

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