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Rare Hereditary Cancers pp 17–27Cite as

Diagnosis and Management of Hereditary Meningioma and Vestibular Schwannoma

Part of the Recent Results in Cancer Research book series (RECENTCANCER,volume 205)

Abstract

Bilateral vestibular schwannomata and meningiomata are the tumours most commonly associated with neurofibromatosis type II (NF2). These tumours may also be seen in patients with schwannomatosis and familial meningioma, but these phenotypes are usually easy to distinguish. The main diagnostic challenge when managing these tumours is distinguishing between sporadic disease which carries low risk of subsequent tumours or NF2 with its associated morbidities and reduced life expectancy. This chapter outlines some of the diagnostic and management considerations along with associated evidence.

Keywords

  • Vestibular schwannoma
  • Meningioma
  • Neurofibromatosis type II
  • NF2
  • Schwannomatosis

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Authors and Affiliations

  1. Department of Clinical Genetics, Guy’s and St Thomas’ NHS Foundation Trust, London, UK

    Adam Shaw

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  1. Adam Shaw
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Correspondence to Adam Shaw .

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Editors and Affiliations

  1. London Bridge Hospital, London, United Kingdom

    Gabriella Pichert

  2. University College London, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom

    Chris Jacobs

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Shaw, A. (2016). Diagnosis and Management of Hereditary Meningioma and Vestibular Schwannoma. In: Pichert, G., Jacobs, C. (eds) Rare Hereditary Cancers. Recent Results in Cancer Research, vol 205. Springer, Cham. https://doi.org/10.1007/978-3-319-29998-3_2

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  • DOI: https://doi.org/10.1007/978-3-319-29998-3_2

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-29996-9

  • Online ISBN: 978-3-319-29998-3

  • eBook Packages: MedicineMedicine (R0)

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