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Important Developments in the Management of Fibroproliferative Scars and Contractures After Burn Injury

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Burn Care for General Surgeons and General Practitioners

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Abstract

Severe scarring is a common and significant problem for burn patients who may have recovered from a life-threatening injury only to development severe hypertrophic scarring (HTS) after discharge from hospital, which significantly compromises their function, appearance, and quality of life. The clinical features of HTS, their assessment and measurement after burn injury are outlined. The cellular and molecular features of HTS are presented to assist the clinician’s understanding of the basis for prevention and treatment of HTS post-burn injury. Current therapies based on the pathophysiology of HTS are presented including conservative nonoperative approaches before surgical treatment and newly developing modalities are outlined.

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Acknowledgements

This work was supported by the Firefighters’ Burn Trust Fund of the University of Alberta Hospital, the Canadian Institutes for Health Research, and the Alberta Heritage Trust Fund for Medical Research.

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Authors and Affiliations

  1. Division of Plastic and Reconstructive Surgery, University of Alberta, 2D2.31 WMC, 8440-112 Street, Edmonton, AB, Canada, T6G 2B7

    Kevin Mowbrey B.M.Sc., M.D. & Geneviève Ferland-Caron M.D., F.R.C.S.C.

  2. Division of Plastic and Reconstructive Surgery and Critical Care, Department of Surgery, University of Alberta, 2D2.31 WMC, 8440-112 Street, Edmonton, AB, Canada, T6G 2B7

    Edward E. Tredget M.D., M.Sc., F.R.C.S.C.

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  1. Kevin Mowbrey B.M.Sc., M.D.
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  2. Geneviève Ferland-Caron M.D., F.R.C.S.C.
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  3. Edward E. Tredget M.D., M.Sc., F.R.C.S.C.
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Correspondence to Edward E. Tredget M.D., M.Sc., F.R.C.S.C. .

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Editors and Affiliations

  1. Univ. of California, Davis Med. Center, Shriners Hosp for Children N California, Sacramento, California, USA

    David G. Greenhalgh

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Mowbrey, K., Ferland-Caron, G., Tredget, E.E. (2016). Important Developments in the Management of Fibroproliferative Scars and Contractures After Burn Injury. In: Greenhalgh, D. (eds) Burn Care for General Surgeons and General Practitioners . Springer, Cham. https://doi.org/10.1007/978-3-319-29161-1_20

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  • DOI: https://doi.org/10.1007/978-3-319-29161-1_20

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