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Efficiency of Non-label Optical Biosensors for the Express Control of Toxic Agents in Food

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Biosensors for Security and Bioterrorism Applications

Abstract

This chapter is devoted to the analysis of the efficiency of a different types of the immune biosensors for the control of toxic agents among of environmental objects, The main attention is paid to the non-labeled immune biosensors and, in particular, optical ones. Among them the immune biosensors based on the porous silicon (PS), surface plasmon resonance (SPR) and total reflection internal ellipsometry (TIRE) are detailed considered. In additional to, the immune biosensors based on calorimeter and thermistors as well as on the piezocristals are described. As model of toxic elements the synthetic chemicals as pesticides and nonylethoxylates as well as the nature biological substances, in particularly, a number of mycotoxins: T2, aflatoxins, patulin and others are used. It is necessary, to underline that the analysis was fulfilled with the model solutions and with real samples: some corn, vegetables and fruits. At the end of the chapter the perspectives of the developed instrumental analytical devices based on the principles of biosensorics are analyzed. Especially it draws attention to the development of multi-parameter portable biosensors based on the basis of the nano-structured porous silicon (nano-PS) from one side and on the artificial selective template surface, calyx(4)arenas and aptamers.

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Acknowledgments

This work was partially supported by EU funded BIOSENSORS-AGRICULT project (Development of nanotechnology based biosensors for agriculture FP7-PEOPLE-2012-IRSES, contract N. 318520) and NATO multi-year Science for Peace Project NUKR.SFPP 984637—“Development of Optical Bio-Sensors for Detection of Bio-Toxins” as well as National University of Life and Environmental Sciences of Ukraine, projects “Development of new generation of the instrumental analytical approaches based on the principles of nano-biotechnology and biosensorics for providing systems of biosafety” and “Creation of effective methods for the construction of artificial selective sites for the instrumental analytical devices of new generation based on the principles of biosensorics”, N 110/476-Appl. and № 110/71-fund., appropriate.

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  1. Laboratory of Biosensorics, National University of Life and Environmental Sciences of Ukraine, 5, Geroyiv Oborony, Kyiv, 03041, Ukraine

    Nickolaj F. Starodub & Nelja F. Shpirka

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  1. Nickolaj F. Starodub
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Correspondence to Nickolaj F. Starodub .

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  1. University of Athens, Athens, Greece

    Dimitrios P. Nikolelis

  2. Lab. of Inorganic & Analytic Chemistry, National Technical University of Athens, Athens, Greece

    Georgia-Paraskevi Nikoleli

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Starodub, N.F., Shpirka, N.F. (2016). Efficiency of Non-label Optical Biosensors for the Express Control of Toxic Agents in Food. In: Nikolelis, D., Nikoleli, GP. (eds) Biosensors for Security and Bioterrorism Applications. Advanced Sciences and Technologies for Security Applications. Springer, Cham. https://doi.org/10.1007/978-3-319-28926-7_18

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