Skip to main content

Perioperative Medicine: Defining the Anesthesiologist’s Role in Shaping Perioperative Outcomes

  • Chapter
  • First Online:
Book cover Perioperative Medicine – Current Controversies

Abstract

The practice of anesthesia has long been regarded as an assistive service for surgery rather than one that, by itself, represents an entity of medical interventions with significant outcome consequences. Only relatively recently, researchers have supplied convincing evidence that anesthesia-related factors impact on outcomes beyond intraoperative care parameters and postoperative pain measures. Specifically, the choice of anesthetic technique may influence major morbidity and mortality, recovery time, length of hospital stay, functional outcomes, long-term quality of life, and economic aspects of care. However, with research in the field evolving, the magnitude of these effects is poorly defined and thus considerable controversy persists. This chapter seeks to introduce the reader to the current literature and to highlight areas where anesthesia related factors have been suggested to significantly impact perioperative outcomes. The presentation focuses largely on the orthopedic patient population, a group that has been most extensively studied. A view of how anesthetic practice may impact on the wider public health system evolves from this presentation.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Fleischut PM, Mazumdar M, Memtsoudis SG (2013) Perioperative database research: possibilities and pitfalls. Br J Anaesth 111(4):532–534

    Article  CAS  PubMed  Google Scholar 

  2. Moskowitz A, McSparron J, Stone DJ, Celi LA (2015) Preparing a new generation of clinicians for the era of big data. Harv Med Stud Rev 2(1):24–27

    PubMed  PubMed Central  Google Scholar 

  3. Rodgers A, Walker N, Schug S et al (2000) Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised trials. BMJ 321(7275):1493

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Macfarlane AJ, Prasad GA, Chan VW, Brull R (2009) Does regional anesthesia improve outcome after total knee arthroplasty? Clin Orthop Relat Res 467(9):2379–2402

    Article  PubMed  PubMed Central  Google Scholar 

  5. Hu S, Zhang ZY, Hua YQ, Li J, Cai ZD (2009) A comparison of regional and general anaesthesia for total replacement of the hip or knee: a meta-analysis. J Bone Joint Surg Br 91(7):935–942

    Article  CAS  PubMed  Google Scholar 

  6. Memtsoudis SG, Sun X, Chiu YL et al (2013) Perioperative comparative effectiveness of anesthetic technique in orthopedic patients. Anesthesiology 118(5):1046–1058

    Article  PubMed  PubMed Central  Google Scholar 

  7. Basques BA, Toy JO, Bohl DD, Golinvaux NS, Grauer JN (2015) General compared with spinal anesthesia for total hip arthroplasty. J Bone Joint Surg Am 97(6):455–461

    Article  PubMed  Google Scholar 

  8. Pugely AJ, Martin CT, Gao Y, Mendoza-Lattes S, Callaghan JJ (2013) Differences in short-term complications between spinal and general anesthesia for primary total knee arthroplasty. J Bone Joint Surg Am 95(3):193–199

    Article  PubMed  Google Scholar 

  9. Memtsoudis SG, Ma Y, González Della Valle A et al (2009) Perioperative outcomes after unilateral and bilateral total knee arthroplasty. Anesthesiology 111(6):1206–1216

    Article  PubMed  PubMed Central  Google Scholar 

  10. Stundner O, Chiu YL, Sun X et al (2012) Comparative perioperative outcomes associated with neuraxial versus general anesthesia for simultaneous bilateral total knee arthroplasty. Reg Anesth Pain Med 37(6):638–644

    Article  PubMed  PubMed Central  Google Scholar 

  11. American Society of Anesthesiologists Task Force on Perioperative Management of patients with obstructive sleep apnea (2014) Practice guidelines for the perioperative management of patients with obstructive sleep apnea: an updated report by the American Society of Anesthesiologists Task Force on Perioperative Management of patients with obstructive sleep apnea. Anesthesiology 120(2):268–286

    Article  Google Scholar 

  12. Memtsoudis SG, Stundner O, Rasul R et al (2013) Sleep apnea and total joint arthroplasty under various types of anesthesia: a population-based study of perioperative outcomes. Reg Anesth Pain Med 38(4):274–281

    Article  PubMed  PubMed Central  Google Scholar 

  13. Memtsoudis SG, Rasul R, Suzuki S et al (2014) Does the impact of the type of anesthesia on outcomes differ by patient age and comorbidity burden? Reg Anesth Pain Med 39(2):112–119

    Article  CAS  PubMed  Google Scholar 

  14. Neuman MD, Silber JH, Elkassabany NM, Ludwig JM, Fleisher LA (2012) Comparative effectiveness of regional versus general anesthesia for hip fracture surgery in adults. Anesthesiology 117(1):72–92

    Article  CAS  PubMed  Google Scholar 

  15. Neuman MD, Rosenbaum PR, Ludwig JM, Zubizarreta JR, Silber JH (2014) Anesthesia technique, mortality, and length of stay after hip fracture surgery. JAMA 311(24):2508–2517

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Patorno E, Neuman MD, Schneeweiss S, Mogun H, Bateman BT (2014) Comparative safety of anesthetic type for hip fracture surgery in adults: retrospective cohort study. BMJ 348:g4022

    Article  PubMed  PubMed Central  Google Scholar 

  17. Stundner O, Rasul R, Chiu YL et al (2014) Peripheral nerve blocks in shoulder arthroplasty: how do they influence complications and length of stay? Clin Orthop Relat Res 472(5):1482–1488

    Article  PubMed  PubMed Central  Google Scholar 

  18. Poeran J, Yeo H, Rasul R, Opperer M, Memtsoudis SG, Mazumdar M (2015) Anesthesia type and perioperative outcome: open colectomies in the United States. J Surg Res 193(2):684–692

    Article  PubMed  Google Scholar 

  19. Ozbek U, Poeran J, Mazumdar M, Memtsoudis SG (2015) Patient safety and comparative effectiveness of anesthetic technique in open lung resections. Chest 148(3):722–730

    Google Scholar 

  20. Stundner O, Ortmaier R, Memtsoudis SG (2014) Which outcomes related to regional anesthesia are most important for orthopedic surgery patients? Anesthesiol Clin 32(4):809–821

    Article  PubMed  Google Scholar 

  21. Bernucci F, Carli F (2012) Functional outcome after major orthopedic surgery: the role of regional anesthesia redefined. Curr Opin Anaesthesiol 25(5):621–628

    Article  PubMed  Google Scholar 

  22. Cassinello F, Prieto I, Del Olmo M, Rivas S, Strichartz GR (2015) Cancer surgery: how may anesthesia influence outcome? J Clin Anesth

    Google Scholar 

  23. Chen WK, Miao CH (2013) The effect of anesthetic technique on survival in human cancers: a meta-analysis of retrospective and prospective studies. PLoS One 8(2), e56540

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  24. Cakmakkaya OS, Kolodzie K, Apfel CC, Pace NL (2014) Anaesthetic techniques for risk of malignant tumour recurrence. Cochrane Database Syst Rev (11):CD008877

    Google Scholar 

  25. Liu J, Ma C, Elkassabany N, Fleisher LA, Neuman MD (2013) Neuraxial anesthesia decreases postoperative systemic infection risk compared with general anesthesia in knee arthroplasty. Anesth Analg 117(4):1010–1016

    Article  PubMed  PubMed Central  Google Scholar 

  26. Chang CC, Lin HC, Lin HW, Lin HC (2010) Anesthetic management and surgical site infections in total hip or knee replacement: a population-based study. Anesthesiology 113(2):279–284

    Article  PubMed  Google Scholar 

  27. Katz J, Clarke H, Seltzer Z (2011) Review article: preventive analgesia: quo vadimus? Anesth Analg 113(5):1242–1253

    Article  PubMed  Google Scholar 

  28. Andreae MH, Andreae DA (2013) Regional anaesthesia to prevent chronic pain after surgery: a Cochrane systematic review and meta-analysis. Br J Anaesth 111(5):711–720

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  29. Carson JL, Terrin ML, Noveck H et al (2011) Liberal or restrictive transfusion in high-risk patients after hip surgery. N Engl J Med 365(26):2453–2462

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  30. Salpeter SR, Buckley JS, Chatterjee S (2014) Impact of more restrictive blood transfusion strategies on clinical outcomes: a meta-analysis and systematic review. Am J Med 127(2):124–131.e3

    Article  CAS  PubMed  Google Scholar 

  31. Guay J (2006) The effect of neuraxial blocks on surgical blood loss and blood transfusion requirements: a meta-analysis. J Clin Anesth 18(2):124–128

    Article  PubMed  Google Scholar 

  32. Kiss H, Raffl M, Neumann D, Hutter J, Dorn U (2005) Epinephrine-augmented hypotensive epidural anesthesia replaces tourniquet use in total knee replacement. Clin Orthop Relat Res 436:184–189

    Article  PubMed  Google Scholar 

  33. Sharrock NE, Mineo R, Urquhart B, Salvati EA (1993) The effect of two levels of hypotension on intraoperative blood loss during total hip arthroplasty performed under lumbar epidural anesthesia. Anesth Analg 76(3):580–584

    CAS  PubMed  Google Scholar 

  34. Perel P, Ker K, Morales Uribe CH, Roberts I (2013) Tranexamic acid for reducing mortality in emergency and urgent surgery. Cochrane Database Syst Rev (1):CD010245

    Google Scholar 

  35. Poeran J, Rasul R, Suzuki S et al (2014) Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety. BMJ 349:g4829

    Article  PubMed  PubMed Central  Google Scholar 

  36. Devereaux PJ, Yang H, Yusuf S et al (2008) Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial. Lancet 371(9627):1839–1847

    Article  CAS  PubMed  Google Scholar 

  37. Blessberger H, Kammler J, Domanovits H et al. (2014) Perioperative beta-blockers for preventing surgery-related mortality and morbidity. Cochrane Database Syst Rev (9):CD004476

    Google Scholar 

  38. Collard CD, Body SC, Shernan SK, Wang S, Mangano DT (2006) Preoperative statin therapy is associated with reduced cardiac mortality after coronary artery bypass graft surgery. J Thorac Cardiovasc Surg 132(2):392–400

    Article  CAS  PubMed  Google Scholar 

  39. Sanders RD, Nicholson A, Lewis SR, Smith AF, Alderson P (2013) Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery. Cochrane Database Syst Rev (7):CD009971

    Google Scholar 

  40. Devereaux PJ, Mrkobrada M, Sessler DI et al (2014) Aspirin in patients undergoing noncardiac surgery. N Engl J Med 370(16):1494–1503

    Article  CAS  PubMed  Google Scholar 

  41. Devereaux PJ, Sessler DI, Leslie K et al (2014) Clonidine in patients undergoing noncardiac surgery. N Engl J Med 370(16):1504–1513

    Article  CAS  PubMed  Google Scholar 

  42. Weiser TG, Regenbogen SE, Thompson KD et al (2008) An estimation of the global volume of surgery: a modelling strategy based on available data. Lancet 372(9633):139–144

    Article  PubMed  Google Scholar 

  43. Martin J, Cheng D (2013) Role of the anesthesiologist in the wider governance of healthcare and health economics. Can J Anaesth 60(9):918–928

    Article  PubMed  Google Scholar 

  44. Duncan CM, Hall Long K, Warner DO, Hebl JR (2009) The economic implications of a multimodal analgesic regimen for patients undergoing major orthopedic surgery: a comparative study of direct costs. Reg Anesth Pain Med 34(4):301–307

    Article  PubMed  Google Scholar 

  45. Macario A, McCoy M (2003) The pharmacy cost of delivering postoperative analgesia to patients undergoing joint replacement surgery. J Pain 4(1):22–28

    Article  PubMed  Google Scholar 

  46. Mariano ER, Chu LF, Peinado CR, Mazzei WJ (2009) Anesthesia-controlled time and turnover time for ambulatory upper extremity surgery performed with regional versus general anesthesia. J Clin Anesth 21(4):253–257

    Article  PubMed  PubMed Central  Google Scholar 

  47. Cannesson M, Kain Z (2015) The Perioperative Surgical Home: An Innovative Clinical Care Delivery Model. J Clin Anesth 27(3):185–187

    Google Scholar 

  48. Kash BA, Zhang Y, Cline KM, Menser T, Miller TR (2014) The perioperative surgical home (PSH): a comprehensive review of US and non-US studies shows predominantly positive quality and cost outcomes. Milbank Q 92(4):796–821

    Article  PubMed  PubMed Central  Google Scholar 

  49. American Society of Anesthesiologists. Perioperative surgical home. https://www.asahq.org/psh. Accessed 05 Apr 2015

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Stavros G. Memtsoudis MD, PhD .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Stundner, O., Memtsoudis, S.G. (2016). Perioperative Medicine: Defining the Anesthesiologist’s Role in Shaping Perioperative Outcomes. In: Stuart-Smith, K. (eds) Perioperative Medicine – Current Controversies. Springer, Cham. https://doi.org/10.1007/978-3-319-28821-5_1

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-28821-5_1

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28819-2

  • Online ISBN: 978-3-319-28821-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics