Donor-Derived Infections: Incidence, Prevention, and Management

  • Nicole Theodoropoulos
  • Michael G. Ison


Organ donors reflect the diverse US population, and there are an increasing number of donors born in, who have resided in, or who have traveled to underdeveloped areas of the world or areas with geographically restricted infections. As such, these donors are exposed to pathogens that can potentially be transmitted to recipients of the donor’s organs. Additionally, there are newer techniques to identify many pathogens that may be transmitted from the donor to the transplant recipients. Finally, high-profile reports of several donor-derived infections have heightened awareness of donor-derived infections and have likely contributed to increased recognition. In this chapter, the incidence, methods of identification and prevention, and management of unexpected donor-derived infections will be reviewed.


Donor-derived infection Donor-derived transmission Organ donor screening Increased risk donor Endemic infection 


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Copyright information

© Springer International Publishing Switzerland 2016

Open Access This chapter is distributed under the terms of the Creative Commons Attribution Noncommercial License, which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

Authors and Affiliations

  1. 1.Internal Medicine/Infectious DiseasesThe Ohio State UniversityColumbusUSA
  2. 2.Divisions of Infectious Diseases and OrganTransplantationNorthwestern University Feinberg School of MedicineChicagoUSA

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