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Cystic Lesions of the Pancreas

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Pancreas and Biliary Disease

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Abstract

Pancreatic cystic lesions (PCL) are relatively rare and in recent years they are being increasingly recognized with the improvement and widespread use of cross-sectional imaging tools. The diagnosis, differentiation, and management of PCL are mandatory since they may carry malignant potentials. PCL are usually diagnosed incidentally on conventional imaging tools including ultrasonography, computed tomography, or magnetic resonance imaging; however, these modalities still have a limited ability to differentiate a benign lesion from malignant. With the high-resolution capacity and better imaging characteristics, endoscopic ultrasonography is superior to these conventional methods. Endoscopic ultrasonography guided fine-needle aspiration provides biochemical, cytological, and DNA analysis of the cystic fluid, which might better determine the lesion. Surgical resection, endoscopic treatment, and follow-up conservatively are the options for treatment. Further diagnostic tools and techniques are still needed to resolve the gray zones in the management and treatment of these lesions.

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Abbreviations

BD-IPMN:

Branch-duct intraductal papillary mucinous neoplasm

CEA:

Serum carcinoembryonic antigen

CLE:

Confocal laser endomicroscopy

CPEN:

Cystic pancreatic endocrine neoplasms

CT:

Computed tomography

ERCP:

Endoscopic retrograde cholangiopancreatography

EUS:

Endoscopic ultrasonography

EUS-FNA:

Endoscopic ultrasound guided fine needle aspiration

FNA:

Fine-needle aspiration

IPMN:

Intraductal papillary mucinous neoplasm

MCN:

Mucinous cystic neoplasm

MDCT:

Multidetector CT

MD-IPMN:

Main-duct intraductal papillary mucinous neoplasm

MR:

Magnetic resonance

MRCP:

Magnetic resonance cholangiopancreatography

PCL:

Pancreatic cystic lesions

PCN:

Pancreatic cystic neoplasms

RFA:

Radiofrequency ablation

SCN:

Serous cystic neoplasm

SPN:

Solid pseudopapillary neoplasm

US:

Ultrasonography

VHL:

von Hippel–Lindau disease

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Authors and Affiliations

  1. Pancreas Biliary Center, Gastrointestinal Unit, Massachusetts General Hospital, 55 Fruit St., Boston, MA, 02114, USA

    Omer Basar M.D. & William R. Brugge M.D.

  2. Department of Gastroenterology, University of Hacettepe, Ankara, Turkey

    Omer Basar M.D.

Authors
  1. Omer Basar M.D.
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  2. William R. Brugge M.D.
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Correspondence to William R. Brugge M.D. .

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Editors and Affiliations

  1. Division of Gastroenterology & Hepatology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA

    Kulwinder Dua

  2. Division of Gastroenterology & Hepatology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA

    Reza Shaker

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Basar, O., Brugge, W.R. (2016). Cystic Lesions of the Pancreas. In: Dua, K., Shaker, R. (eds) Pancreas and Biliary Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-28089-9_8

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  • DOI: https://doi.org/10.1007/978-3-319-28089-9_8

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