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14 Special Aspects of Fungal Catabolic and Anabolic Pathways

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Biochemistry and Molecular Biology

Part of the book series: The Mycota ((MYCOTA,volume III))

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Abstract

This chapter deals with differences among fungi to solve specific metabolic problems. Although metabolic studies have mainly been performed on Ascomycetes, it is shown that even closely related species developed different solutions to cope with specific nutritional conditions. Especially, fungal morphology (yeast versus hyphae), the natural nutritional niches, gene loss and acquisition and organismal interaction led to a very large variety of metabolic pathways. To exemplify these variations, an emphasis is given on the degradation of the toxic metabolic intermediate propionyl-CoA, the difference in utilisation of gluconeogenic nutrient sources among yeasts and filamentous fungi, the ability of using histidine as a nitrogen source and the biosynthesis of the amino acid lysine that also provides the essential precursor alpha-aminoadipate for synthesis of penicillins and cephalosporins.

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Authors and Affiliations

  1. Microbial Biochemistry and Physiology, Leibniz Institute for Natural Product Research and Infection Biology e. V., -Hans Knöll Institute, Beutenbergstraße 11a, 07745, Jena, Germany

    Matthias Brock & Elena Geib

  2. Institute for Microbiology, Friedrich Schiller University Jena, 07743, Jena, Germany

    Matthias Brock

  3. Fungal Genetics and Biology Group, School of Life Sciences, University of Nottingham, University Park, NG7 2RD, Nottingham, UK

    Matthias Brock & Elena Geib

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  1. Matthias Brock
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Correspondence to Matthias Brock .

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  1. Pharmazeutische Mikrobiologie, Friedrich-Schiller-Universität, Jena, Germany

    Dirk Hoffmeister

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© 2016 Springer International Publishing Switzerland

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Brock, M., Geib, E. (2016). 14 Special Aspects of Fungal Catabolic and Anabolic Pathways. In: Hoffmeister, D. (eds) Biochemistry and Molecular Biology. The Mycota, vol III. Springer, Cham. https://doi.org/10.1007/978-3-319-27790-5_14

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