Sepsis and Multiple Organ Failure

  • Jean-Charles PreiserEmail author
  • Vincent Fraipont


Signs of sepsis are systematically present in each critically ill patient after a few days of stay in an intensive care unit.The associated metabolic response includes a rise in expended energy a few after its onset and changes in the use of energy substrates. General recommendations include the preference of the oral or enteral route and a limitation of the caloric intake during the early phase. Nutritional interventions have been assessed to modulate the inflammatory response underlying the metabolic changes, including the addition of supplemental omega-3 fatty acids, glutamine and antioxidants. The beneficial effects of these interventions started during the course of critical illness have not been convincingly confirmed. Hence, no specific diet or nutritional formula is currently recommended.


Severe Sepsis Septic Patient Nutritional Intervention Energy Substrate Glutathione Peroxidase Enzyme 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Department of Intensive CareErasme University Hospital, Free University of BrusselsBrusselsBelgium
  2. 2.Intensive CareCentre hospitalier regional La CitadelleLiegeBelgium

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