Abstract
Spleen is involved in approximately one third of patients with non-Hodgkin lymphoma (NHL), usually secondarily, either at presentation or at the time of disease progression. On the contrary, primary splenic lymphoma is rare, comprising only 1 % of all lymphomas, although its incidence is probably underestimated. The definition of primary splenic lymphoma is controversial. Herein, we adopt a less restrictive definition of splenic lymphomas, encompassing cases presenting with splenic involvement and in which the disease may also extend to the bone marrow, blood, and liver without prominent lymphadenopathy. Splenic lymphomas include mainly the following categories: splenic marginal zone lymphoma (SMZL), hairy cell leukemia (HCL), and the provisional entities: HCL variant (HCLv), splenic diffuse red pulp small B-cell lymphoma (SDRPL), primary splenic diffuse large B-cell lymphoma (DLBCL), and Τ-γδ hepatosplenic lymphoma [1].
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Kalpadakis, C., Pangalis, G.A., Kechagias, D.T., Yiakoumis, X., Vlachou, F.J. (2016). Splenic Lymphomas. In: Andreou, J., Kosmidis, P., Gouliamos, A. (eds) PET/CT in Lymphomas. Springer, Cham. https://doi.org/10.1007/978-3-319-27380-8_12
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DOI: https://doi.org/10.1007/978-3-319-27380-8_12
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