Abstract
In this chapter, we will briefly describe the complexity of the main mechanical, biochemical and physicochemical phenomena that occur in the mouth during food consumption using examples. To better understand the reactions occurring in the mouth during food consumption, in vitro systems called model mouths were developed to simulate food consumption and thus answer some of the more fundamental questions regarding olfactory perception. This chapter provides examples of the applications of the model mouth in performing oral functions, such as mastication, saliva production and airflow, as well as swallowing, while the released volatile compounds are measured. The recent model mouth designs represent the actual occurrence of food consumption under oral conditions in a more accurate way. We believe that this type of methodology will be even more commonly applied in the future to improve the knowledge in this field.
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- APCI:
-
atmospheric pressure chemical ionization
- API-MS:
-
atmospheric pressure ionization mass spectrometry
- GC-FID:
-
gas chromatography with flame-ionization detection
- GC:
-
gas chromatography
- PEEK:
-
polyether ether ketone
- PTR:
-
proton transfer reaction
- RAS:
-
retronasal aroma simulator
- SPME:
-
solid phase micro extraction
- VOC:
-
volatile organic compound
References
J.S. Chen: Food oral processing – A review, Food Hydrocolloids 23, 1–25 (2009)
C. Salles, M.C. Chagnon, G. Feron, E. Guichard, H. Laboure, M. Morzel, E. Semon, A. Tarrega, C. Yven: In-mouth mechanisms leading to flavor release and perception, Crit. Rev. Food Sci. 51, 67–90 (2011)
P. Morell, I. Hernando, S.M. Fiszman: Understanding the relevance of in-mouth food processing. A review of in vitro techniques, Trends Food Sci. Technol. 35, 18–31 (2014)
J.R. Piggott, C.J. Schaschke: Release cells, breath analysis and in-mouth analysis in favour research, Biomol. Eng. 17, 129–136 (2001)
J.F. Prinz, P.W. Lucas: An optimization model for mastication and swallowing in mammals, Proc. R. Soc. B 264, 1715–1721 (1997)
L. Engelen, R.A. de Wijk, J.F. Prinz, A.M. Janssen, H. Weenen, F. Bosman: The effect of oral and product temperature on the perception of flavor and texture attributes of semi-solids, Appetite 41, 273–281 (2003)
A. van der Bilt, H.W. van der Glas, F. Mowlana, M.R. Heath: A comparison between sieving and optical scanning for the determination of particle size distributions obtained by mastication in man, Arch. Oral Biol. 38, 159–162 (1993)
K.R. Agrawal, P.W. Lucas, I.C. Bruce, J.F. Prinz: Food properties that influence neuromuscular activity during human mastication, J. Dent. Res. 77, 1931–1938 (1998)
L. Mioche, P. Bourdiol, S. Monier: Chewing behaviour and bolus formation during mastication of meat with different textures, Arch. Oral Biol. 48, 193–200 (2003)
L. Engelen, A. Fontijn-Tekamp, A. van der Bilt: The influence of product and oral characteristics on swallowing, Arch. Oral Biol. 50, 739–746 (2005)
K.R. Agrawal, P.W. Lucas, I.C. Bruce: The effects of food fragmentation index on mandibular closing angle in human mastication, Arch. Oral Biol. 45, 577–584 (2000)
W.E. Brown, D. Eves, M. Ellison, D. Braxton: Use of combined electromyography and kinesthesiology during mastication to chart the oral breakdown of foodstuffs: Relevance to measurement of food texture, J. Texture Stud. 29, 145–167 (1998)
K. Kohyama, L. Mioche: Chewing behavior observed at different stages of mastication for six foods, studied by electromyography and jaw kinematics in young and elderly subjects, J. Texture Stud. 35, 395–414 (2004)
W.E. Brown, K.R. Langley, L. Mioche, S. Marie, S. Gérault, D. Braxton: Individuality of understanding and assessment of sensory atttributes of foods, in particular, tenderness of meat, Food Qual. Prefer. 7, 205–216 (1996)
K. Kohyama, L. Mioche, J.F. Martin: Chewing patterns of various texture foods studied by electromyography in young and elderly populations, J. Texture Stud. 33, 269–283 (2002)
A.M. Haahr, A. Bardow, C.E. Thomsen, S.B. Jensen, B. Nauntofte, M. Bakke, J. Adler-Nissen, W.L.P. Bredie: Release of peppermint flavour compounds from chewing gum: Effect of oral functions, Physiol. Behav. 82, 531–540 (2004)
G. Lawrence, S. Buchin, C. Achilleos, F. Bérodier, C. Septier, P. Courcoux, C. Salles: In vivo sodium release and saltiness perception in solid lipoprotein matrices. 1. Effect of composition and texture, J. Agric. Food Chem. 60, 5287–5298 (2012)
G. Lawrence, C. Septier, C. Achilleos, P. Courcoux, C. Salles: In vivo sodium release and saltiness perception in solid lipoprotein matrices. 2. Impact of oral parameters, J. Agric. Food Chem. 60, 5299–5306 (2012)
V.A. Phan, C. Yven, G. Lawrence, C. Chabanet, J.-M. Reparet, C. Salles: In vivo sodium release related to salty perception during eating model cheeses of different texture, Int. Dairy J. 18, 956–963 (2008)
A. Tarrega, C. Yven, E. Semon, C. Salles: Aroma release and chewing activity during eating different model cheeses, Int. Dairy J. 16, 849–857 (2007)
A. Tarrega, C. Yven, E. Semon, C. Salles: In-mouth aroma compound release during cheese consumption: Relationship with food bolus formation, Int. Dairy J. 21, 358–364 (2011)
A. Buettner, A. Beer, C. Hannig, M. Settles: Observation of the swallowing process by application of videofluoroscopy and real-time magnetic resonance imaging-consequences for retronasal aroma stimulation, Chem. Senses 26, 1211–1219 (2001)
M. Hodgson, R.S.T. Linforth, A.J. Taylor: Simultaneous real-time measurements of mastication, swallowing, nasal airflow, and aroma release, J. Agric. Food Chem. 51, 5052–5057 (2003)
M. Repoux, E. Semon, G. Feron, E. Guichard, H. Laboure: Inter-individual variability in aroma release during sweet mint consumption, Flavour Frag. J. 27, 40–46 (2012)
C. Yven, J. Patarin, A. Magnin, H. Labouré, M. Repoux, E. Guichard, G. Feron: Consequences of individual chewing strategies on bolus rheological properties at the swallowing threshold, J. Texture Stud. 43, 309–318 (2012)
M. Repoux, H. Laboure, P. Courcoux, I. Andriot, E. Semon, C. Yven, G. Feron, E. Guichard: Combined effect of cheese characteristics and food oral processing on in vivo aroma release, Flavour Frag. J. 27, 414–423 (2012)
E. Neyraud: Role of saliva in oral food perception. In: Saliva: Secretion and Functions, ed. by A.J.M. Ligtenberg, E.C.I. Veerman (Karger, Basel 2014)
E.N. Friel, A.J. Taylor: Effect of salivary components on volatile partitioning from solutions, J. Agric. Food Chem. 49, 3898–3905 (2001)
A. Buettner: Influence of human saliva on odorant concentrations. 2. Aldehydes, alcohols, 3-alkyl-2-methoxypyrazines, methoxyphenols, and 3-hydroxy-4,5-dimethyl-2(5H)-furanone, J. Agric. Food Chem. 50, 7105–7110 (2002)
A. Buettner: Influence of human salivary enzymes on odorant concentration changes occurring in vivo. 1. Esters and thiols, J. Agric. Food Chem. 50, 3283–3289 (2002)
A. Genovese, P. Piombino, A. Gambuti, L. Moio: Simulation of retronasal aroma of white and red wine in a model mouth system. Investigating the influence of saliva on volatile compound concentrations, Food Chem. 114, 100–107 (2009)
A.L. Ferry, J. Hort, J.R. Mitchell, S. Lagarrigue, B.V. Pamies: Effect of amylase activity on starch paste viscosity and its implications for flavor perception, J. Texture Stud. 35, 511–524 (2004)
A.L. Ferry, J.R. Mitchell, J. Hort, S.E. Hill, A.J. Taylor, S. Lagarrigue, B. Valles-Pamies: In-mouth amylase activity can reduce perception of saltiness in starch-thickened foods, J. Agric. Food Chem. 54, 8869–8873 (2006)
E. Neyraud, O. Palicki, C. Schwartz, S. Nicklaus, G. Feron: Variability of human saliva composition: Possible relationships with fat perception and liking, Arch. Oral Biol. 57, 556–566 (2012)
J. Poette, J. Mekoué, C. Genot, E. Neyraud, O. Berdeaux, A. Renault, E. Guichard, C. Genot, G. Feron: Fat sensitivity in human: Oleic acid detection thresholds in model emulsion is linked to saliva composition and oral volume, Flavour Frag. J. 29, 39–49 (2013)
S.M. van Ruth, J.P. Roozen: Influence of mastication and saliva on aroma release in a model mouth system, Food Chem. 71, 339–345 (2000)
K.D. Jensen, H.C. Beck, L. Jeppesen, M.R. Nørrelykke, A.M. Hansen: A new system for dynamic measurements of flavour release: A combined artificial mouth and membrane inlet mass spectrometer. In: Flavour Research at the Dawn of the Twenty-first Century, ed. by J.L. Le Quéré, P.X. Etiévant (Lavoisier Tec and Doc, Paris 2003)
S.J. Withers, J.M. Conner, J.R. Piggott, A. Paterson: A simulated mouth to study flavor release from alcoholic beverages. In: Food Flavors: Formation, Analysis and Packaging Influences, ed. by E.T. Contis, C.T. Ho, C.J. Mussinan, T.H. Parliment, F. Shahidi, A.M. Spanier (Elsevier Science, Amsterdam 1998)
S.M. van Ruth, J.P. Roozen, J.L. Cozijnsen: Comparison of dynamic headspace mouth model systems for flavor release from rehydrated bell pepper cuttings. In: Trends in Flavour Research, ed. by H. Maarse, D.G. van der Heij (Elsevier Science, Amsterdam 1994)
S. Odake, J.P. Roozen, J.J. Burger: Flavor release of diacetyl and 2-heptanone from cream style dressings in three mouth model systems, Biosci. Biotechnol. Biochem. 64, 2523–2529 (2000)
D.D. Roberts, T.E. Acree: Simulation of retronasal aroma using a modified headspace technique – Investigating the effects of saliva, temperature, shearing, and oil on flavor release, J. Agric. Food Chem. 43, 2179–2186 (1995)
S. Rabe, U. Krings, D.S. Banavara, R.G. Berger: Computerized apparatus for measuring dynamic flavor release from liquid food matrices, J. Agric. Food Chem. 50, 6440–6447 (2002)
A. Woda, A. Mishellany-Dutour, L. Batier, O. François, J.P. Meunier, B. Reynaud, M. Alric, M.A. Peyron: Development and validation of a mastication simulator, J. Biomech. 43, 1667–1673 (2010)
G. Arvisenet, L. Billy, P. Poinot, E. Vigneau, D. Bertrand, C. Prost: Effect of apple particle state on the release of volatile compounds in a new artificial mouth device, J. Agric. Food Chem. 56, 3245–3253 (2008)
C. Salles, A. Tarrega, P. Mielle, J. Maratray, P. Gorria, J. Liaboeuf, J.J. Liodenot: Development of a chewing simulator for food breakdown and the analysis of in vitro flavor compound release in a mouth environment, J. Food Eng. 82, 189–198 (2007)
O. Benjamin, P. Silcock, J.A. Kieser, J.N. Waddell, M.V. Swain, D.W. Everett: Development of a model mouth containing an artificial tongue to measure the release of volatile compounds, Innov. Food Sci. Emerg. Technol. 15, 96–103 (2012)
S. Ishihara, M. Nakauma, T. Funami, S. Odake, K. Nishinari: Swallowing profiles of food polysaccharide gels in relation to bolus rheology, Food Hydrocolloids 25, 1016–1024 (2011)
G.-H. Hui, S.-S. Mi, S.-P. Deng: Sweet and bitter tastant specific detection by the tste cell-based sensor, Biosens. Bioelectron. 35, 429–438 (2012)
C. Yven, S. Guessasma, L. Chaunier, G. Della Valle, C. Salles: The role of mechanical properties of brittle airy foods on the masticatory performance, J. Food Eng. 101, 85–91 (2010)
C. Yven, A. Tarrega, E. Sémon, S. Guessasma, C. Salles: Chewing simulation: A way to understand the relationships between mastication, food breakdown and flavour release. In: Expression of Multidisciplinary Flavour Science, ed. by I. Blank, M. Wüst, C. Yeretzian (Zürcher Hochschule für Angewandte Wissenschaften, Winterthur 2010)
A. Mishellany-Dutour, M.-A. Peyron, J. Croze, O. Francois, C. Hartmann, M. Alric, A. Woda: Comparison of food boluses prepared in vivo and by the AM2 mastication simulator, Food Qual. Prefer. 22, 326–331 (2011)
J.F. Prinz, A.M. Janssen, R.A. de Wijk: In vitro simulation of the oral processing of semi-solid foods, Food Hydrocolloids 21, 397–401 (2007)
T. Mills, F. Spyropoulos, I.T. Norton, S. Bakalis: Development of an in-vitro mouth model to quantify salt release from gels, Food Hydrocolloids 25, 107–113 (2011)
S. Ishihara, M. Nakauma, T. Funami, S. Odake, K. Nishinari: Viscoelastic and fragmentation characters of model bolus from polysaccharide gels after instrumental mastication, Food Hydrocolloids 25, 1210–1218 (2011)
L. Lvova, S. Denis, S. Barra, P. Mielle, C. Salles, C. Vergoignan, C. Di Natale, R. Paolesse, P. Temple-Boyer, G. Feron: Salt release monitoring with specific sensors in in vitro oral and digestive environments from soft cheeses, Talanta 2012, 171–180 (2012)
D. Kennedy, J. Kieser, C. Bolter, M. Swain, B. Singh, J.N. Waddell: Tongue pressure patterns during water swallowing, Dysphagia 25, 11–19 (2010)
T. Ono, K. Hori, T. Nokubi: Pattern of tongue pressure on hard palate during swallowing, Dysphagia 19, 259–264 (2004)
A. Buettner, A. Beer, C. Hannig, M. Settles, P. Schieberle: Physiological and analytical studies on flavor perception dynamics as induced by the eating and swallowing process, Food Qual. Prefer. 13, 497–504 (2002)
K.G.C. Weel, A.E.M. Boelrijk, J.J. Burger, N.E. Claassen, H. Gruppen, A.G.J. Voragen, G. Smit: Effect of whey protein on the in vivo release of aldehydes, J. Agric. Food Chem. 51, 4746–4752 (2003)
K.G.C. Weel, A.E.M. Boelrijk, J.J. Burger, M. Verschueren, H. Gruppen, A.G.J. Voragen, G. Smit: New device to simulate swallowing and in vivo aroma release in the throat from liquid and semiliquid food systems, J. Agric. Food Chem. 52, 6564–6571 (2004)
S.M. van Ruth, K. Buhr: Influence of mastication rate on dynamic flavour release analysed by combined model mouth/proton transfer reaction-mass spectrometry, Int. J. Mass Spectrom. 239, 187–192 (2004)
P. Mielle, A. Tarrega, E. Sémon, J. Maratray, P. Gorria, J.J. Liodenot, J. Liaboeuf, J.L. Andrejewski, C. Salles: From human to artificial mouth, from basics to results, Sens. Actuators B 146, 440–445 (2010)
S. Rabe, U. Krings, R.G. Berger: In vitro study of the influence of physiological parameters on dynamic in-mouth flavour release from liquids, Chem. Senses 29, 153–162 (2004)
O. Benjamin, P. Silcock, J. Beauchamp, A. Buettner, D.W. Everett: Tongue pressure and oral conditions affect volatile release from liquid systems in a model mouth, J. Agric. Food Chem. 60, 9918–9927 (2012)
S. Odake, J.P. Roozen, J.J. Burger: Effect of saliva dilution on the release of diacetyl and 2-heptanone from cream style dressings, Food/Nahrung 42, 385–391 (1998)
P. Poinot, G. Arvisenet, J. Grua-Priol, C. Fillonneau, C. Prost: Use of an artificial mouth to study bread aroma, Food Res. Int. 42, 717–726 (2009)
V. Roger-Leroi, A. Mishellany-Dutour, A. Woda, M. Marchand, M.A. Peyron: Substantiation of an artificial saliva formulated for use in a masticatory apparatus, Odontostomatol Trop. J. 35, 5–14 (2012)
S.M. van Ruth, I. Grossmann, M. Geary, C.M. Delahunty: Interactions between artificial saliva and 20 aroma compounds in water and oil model systems, J. Agric. Food Chem. 49, 2409–2413 (2001)
A.J. Taylor, R.S.T. Linforth, B.A. Harvey, A. Blake: Atmospheric pressure chemical ionisation mass spectrometry for in vivo analysis of volatile flavour release, Food Chem. 71, 327–338 (2000)
Y. Tahara, K. Toko: Electronic tongues – A review, IEEE Sens. J. 13, 3001–3011 (2013)
K. Beullens, P. Mészaros, S. Vermeir, D. Kirsanov, A. Legin, S. Buysens, N. Cap, B.M. Nicolaï, J. Lammertyn: Analysis of tomato taste using two types of electronic tongues, Sens. Actuators B 131, 10–17 (2008)
X. Tian, J. Wang, X. Zhang: Discrimination of preserved licorice apricot using electronic tongue, Math. Comput. Modell. 58, 743–751 (2013)
O. Benjamin, P. Silcock, J. Beauchamp, A. Buettner, D.W. Everett: Volatile release and structural stability of β-lactoglobulin primary and multilayer emulsions under simulated oral conditions, Food Chem. 140, 124–134 (2013)
A. Hansson, P. Giannouli, S. Van Ruth: The influence of gel strength on aroma release from pectin gels in a model mouth and in vivo, monitored with proton-transfer-reaction mass spectrometry, J. Agric. Food Chem. 51, 4732–4740 (2003)
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Salles, C., Benjamin, O. (2017). Models of the Oral Cavity for the Investigation of Olfaction. In: Buettner, A. (eds) Springer Handbook of Odor. Springer Handbooks. Springer, Cham. https://doi.org/10.1007/978-3-319-26932-0_14
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