Abstract
What happens when all the chromosomes are there but in the wrong order or from the wrong parent? Now we can look at individual genes and count them, recognise if they are in the right numbers and right order and use this as a diagnostic tool; just knowing the DNA sequence of a gene is not enough. There is still plenty of life in chromosomes yet.
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References
Callaway E (2013) Most popular human cell in science gets sequenced. Nature 495
Charlesworth B (1991) The evolution of sex chromosomes. Science 251:1030–1033
Dennis C, Gallagher R (2001) The human genome. Nature Palgrave, London
Evans HJ (1982) Chromosomal mutations in human populations. Cytogenet Genome Res 33(1–2):48–56
McKusick VA (1969) Human genetics. Prentice-Hall, Englewood Cliffs, NJ
Rinn J, Guttman M (2014) RNA function. RNA and dynamic nuclear organization. Science (New York, NY) 345(6202):1240–1241
Seuánez HN (1979) The phylogeny of human chromosomes. Springer, Berlin
Skloot R, Turpin B (2010) The immortal life of Henrietta Lacks. Crown Publishers, New York
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Wall, W.J. (2016). What We Know, What We Don’t and Where This May Lead Us. In: The Search for Human Chromosomes. Springer, Cham. https://doi.org/10.1007/978-3-319-26336-6_10
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DOI: https://doi.org/10.1007/978-3-319-26336-6_10
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Online ISBN: 978-3-319-26336-6
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