Abstract
In this chapter we provide an extensive overview about the pathophysiology, clinical diagnosis and treatment of erectile dysfunction. We start with a discussion on the current EAU guidelines on erectile dysfunction. Subsequently, an overview of the essential steps during sexual clinical examination is given and we underline the importance of erectile dysfunction as a predictor of future cardiovascular events. Clinical treatment of erectile dysfunction is described consisting of PDE5-inhibitors as a first-line treatment and intracavernous and intraurethral administration of vasoactive substances and implantation of a penile prosthesis as second- and third-line options.
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Further Reading
Albersen M, et al. The future is today: emerging drugs for the treatment of erectile dysfunction. Expert Opin Emerg Drugs. 2010;15(3):467–80. A review on what to expect from the future therapies for ED.
Corona G, et al. EMAS Study Group. Age-related changes in general and sexual health in middle-aged and older men: results from the European Male Ageing Study (EMAS). J Sex Med. 2010;7(4 Pt 1):1362–80. One of the capital studies on the epidemiology of ED.
Fode M, et al. Penile rehabilitation after radical prostatectomy: what the evidence really says. BJU Int. 2013;112(7):998–1008. Mikkel Fode and coworkers critically revise the evidence for post-prostatectomy penile rehabilitation and conclude that better documentation for current penile rehabilitation and/or better rehabilitation protocols are needed: “One must be careful not to repeat the statement that penile rehabilitation improves erectile function after RP so many times that it becomes a truth even without the proper scientific backing.”
Lue TF. Erectile dysfunction. N Engl J Med. 2000;342(24):1802–13. Excellent review on all aspects of ED by one of the pioneers of ED research.
Nehra A, et al. The Princeton III Consensus recommendations for the management of erectile dysfunction and cardiovascular disease. Mayo Clin Proc. 2012;87(8):766–78. The Princeton III consensus: first emphasizing the use of exercise ability and stress testing to ensure that each man's cardiovascular health is consistent with the physical demands of sexual activity before prescribing treatment for ED, and second highlighting the link between ED and CVD, which may be asymptomatic and may benefit from cardiovascular risk reduction.
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© 2016 Springer International Publishing Switzerland
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Weyne, E., Albersen, M. (2016). Erectile Dysfunction. In: Heesakkers, J., Chapple, C., De Ridder, D., Farag, F. (eds) Practical Functional Urology. Springer, Cham. https://doi.org/10.1007/978-3-319-25430-2_12
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DOI: https://doi.org/10.1007/978-3-319-25430-2_12
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