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Low-Dimensional and Nanostructured Materials and Devices pp 589–607Cite as

Microfluidics and Its Applications in Bionanotechnology

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Part of the book series: NanoScience and Technology ((NANO))

Abstract

Several advantages of microfluidic systems such as rapid control, reduced size, low costs, large-scale integration and in vivo simulation of cellular microenvironments make them suitable for diverse bionanotechnological applications. This chapter reviews major current and potential microfluidic applications in bionanotechnology, including miniaturized devices related to common molecular biological techniques such as polymerase chain reaction (PCR), DNA microarray and electrophoresis; microfluidic bioreactors; and monitoring microbial behaviour by microfluidics. Additionally, present applications and future potential of microfluidics in microbial strain development and single cell analysis/characterization are discussed.

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Acknowledgments

Our research presented in this chapter was supported by the COST Action CM0902, Turkish Scientific and Technological Research Council (TÜBİTAK) (project no: 105T314, 107T284, 109T638, PI: ZPÇ), Istanbul Technical University (ITU) Research Funds (project no: 30108, 34200, PI: ZPÇ). BS is financially supported by the Faculty Member Training Programme (ÖYP) of the Council of Higher Education (YÖK) in Turkey.

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Authors and Affiliations

  1. Department of Molecular Biology & Genetics, Faculty of Science and Letters, Istanbul Technical University, 34469, Maslak, Istanbul, Turkey

    Z. P. Çakar & B. Sönmez

  2. Dr. Orhan Öcalgiray Molecular Biology, Biotechnology and Genetics Research Center (ITU-MOBGAM), Istanbul Technical University, Maslak, Istanbul, 34469, Turkey

    Z. P. Çakar & B. Sönmez

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  1. Z. P. Çakar
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Correspondence to Z. P. Çakar .

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  1. Department of Physics Engineering, Faculty of Science and Letters,, Istanbul Technical University, Istanbul, Türkiye

    Hilmi Ünlü

  2. Department of Physics and Engineering Physics, Stevens Institute of Technology, Hoboken, NJ, USA

    Norman J. M. Horing

  3. Leibniz-Inst. für innovative Mikroelektr, Innovations for High Performance Microelectronics (IHP) GmbH, Frankfurt, Germany

    Jaroslaw Dabrowski

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Çakar, Z.P., Sönmez, B. (2016). Microfluidics and Its Applications in Bionanotechnology. In: Ünlü, H., Horing, N.J.M., Dabrowski, J. (eds) Low-Dimensional and Nanostructured Materials and Devices. NanoScience and Technology. Springer, Cham. https://doi.org/10.1007/978-3-319-25340-4_24

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