Curiouser Binding-Sites – In Membrane Transport Proteins



The idea of a semi-permeable-membrane as the barrier between cell interior and the surrounding space assumed that it is permeable to water but not to the solutes. The membrane surrounding a living cell is indeed permeable to water but it also contains protein entities, aquaporins, that contain pores of high specificity so that an individual water molecule H2O, can pass through it but not the hydrated proton, H3O+. This chapter covers the story of the discovery, structural studies and mechanism of action of the following membrane proteins: of aquaporins, of lac-permease and of voltage-dependent potassium channel.


Potassium Channel Nobel Prize Semipermeable Membrane Purple Membrane Membrane Transport Protein 
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© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.CaesareaIsrael

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