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Fundamentals and Recent Advances in Hydrogen Production and Nitrogen Fixation in Cyanobacteria

  • Namita Khanna
  • Patrícia Raleiras
  • Peter Lindblad
Chapter
Part of the Developments in Applied Phycology book series (DAPH, volume 6)

Abstract

There is an urgent need to develop sustainable solutions to convert solar energy into energy carriers used in the society. In addition to solar cells generating electricity, there are several options to generate solar fuels. Native and engineered cyanobacteria have been as model systems to examine, demonstrate, and develop photobiological hydrogen production. In the present contribution the knowledge and understanding of the native systems in cyanobacteria to generate hydrogen, as well as metabolic modulations and genetic engineering to enhance hydrogen production is presented and summarized. Specifically, the recent insight around ferredoxin/flavodoxin as the likely electron donor to the bidirectional Hox-hydrogenase instead of the generally accepted NAD(P)H is highlighted and discussed. In addition, engineering approaches of [NiFe] hydrogenases for optimal catalytic efficiencies and attempts to express high turnover [FeFe] hydrogenase in cyanobacteria that may facilitate the development of strains to reach target levels of hydrogen production in cyanobacteria are detailed. The fundamental advancements achieved in these fields are summarized in this review.

Keywords

Cyanobacteria Bidirectional hox-hydrogenase Genetic engineering Hydrogen production Hydrogenase Nitrogenase Uptake hydrogenase 

Notes

Acknowledgements

Research in the authors’ laboratory received funding from the Swedish Energy Agency and the Knut and Alice Wallenberg Foundation (project MoSE).

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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Namita Khanna
    • 1
  • Patrícia Raleiras
    • 1
  • Peter Lindblad
    • 1
  1. 1.Microbial Chemistry, Department of Chemistry – Ångström LaboratoryUppsala UniversityUppsalaSweden

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