Lifestyle Therapy as Medicine for the Treatment of Obesity

  • Jamy D. ArdEmail author
  • Gary D. Miller


Obesity is a chronic disease of excess adiposity that affects approximately one-third of the adult population in the USA with a growing prevalence worldwide. Obesity has been one of the most challenging complex diseases because of the overwhelming influence of the obesogenic environment. Despite this challenging environment, lifestyle interventions for obesity can be successful at creating a negative energy balance, the cornerstone of obesity management. The methods of lifestyle therapy for obesity treatment can be individualized to target associated risk factors, enhance adherence to a treatment plan, and lead to sustained maintenance of weight loss. Using dietary modification, physical activity, and behavioral counseling, the practitioner can address the physiological and behavioral underpinnings that contribute to calorie imbalance and excess weight gain. This chapter reviews the components of effective and individualized lifestyle therapy strategies to prevent and treat obesity.


Behavior modification Energy balance Physical activity Diet therapy Built environment Dietary patterns Meal replacements Glycemic index Energy density 



Alpha-Melanocyte-stimulating hormone


Agouti-related peptide


Activity energy expenditure


Body Mass Index


Complete meal replacements


Cardiovascular disease




Edmonton Obesity Staging System


Gastroesophageal reflux disease


Glucagon-like polypeptide-1


High-intensity interval training


Long-chain triglycerides


Medium-chain triglycerides


Motivational interviewing


Meal replacements


National Cholesterol Education Program


National Health and Nutrition Examination Survey


Neuropeptide Y


Nucleus Tractus Solitaries


Partial meal replacements




Randomized controlled trial


Resting energy expenditure


Type-2 diabetes


Total energy expenditure


Thermic effect of feeding


Visceral adipose tissue


Very low-calorie diet


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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Department of Epidemiology and PreventionWake Forest UniversityWinston-SalemUSA
  2. 2.Department of Health and Exercise ScienceWake Forest UniversityWinston-SalemUSA

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