Human Brucellosis and Its Complications

  • George F. ArajEmail author


Brucellosis has been an important zoonotic disease globally. Since Brucella can infect and survive without inducing a massive inflammatory response, this bacteria was labeled as “stealth pathogen.” Its protean and diverse clinical presentation can mimic other infectious and noninfectious diseases, posing challenges to physicians in reaching a diagnosis, and merited the label “disease of mistakes.” The complications of brucellosis are common and can involve a wide range of body organs and localization, neurobrucellosis being among the most serious ones. Awareness about the disease and the use of appropriate Brucella-specific tests can expedite the accurate diagnosis.


Clinical features Complications Diagnosis Human brucellosis 



Brucella-containing vacuoles


Cerebrospinal fluid


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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Department of Pathology and Laboratory MedicineAmerican University of Beirut Medical CenterBeirutLebanon

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