Intramedullary Brucellosis

  • Erdal KalkanEmail author
  • Fatih Erdi
  • Ahmet Tuncay Turgut
  • Bülent Kaya


Human neurobrucellosis has a broad spectrum of clinical manifestations depending on the stage of the infection and affected part of the nervous system. Neurobrucellosis is the second most common and severely debilitating complication of the systemic brucellosis and may occur at any stage, even years after and without the sytemic symptoms. Clinically, neurobrucellosis can present in an acute form as meningitis, meningoencephalitis, myelopathy, or neuropathy; in chronic form as granuloma, demyelinization, or degeneration; or in any combination of these. In this chapter, we analyze the etiology, physiopathology, clinical picture, diagnosis, and management of intramedullary brucellosis in detail.


Abscess Brucella Granuloma Intramedullary Neurobrucellosis 



Cerebrospinal fluid


Computed tomography


Magnetic resonance imaging


Positron emission tomography combined with computed tomography


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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Erdal Kalkan
    • 1
    Email author
  • Fatih Erdi
    • 1
  • Ahmet Tuncay Turgut
    • 2
  • Bülent Kaya
    • 1
  1. 1.Department of NeurosurgeryNecmettin Erbakan University, Meram Faculty of MedicineKonyaTurkey
  2. 2.Department of RadiologyHacettepe University School of MedicineAnkaraTurkey

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