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Brucellar Spondylitis as a Complication of Brucellosis

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Neurobrucellosis

Abstract

Brucellosis, being a systemic disease, may affect many organ systems. The involvement of the musculoskeletal involvement is associated with 10–85 % of the focal complications. Spinal involvement is one of the most commonly encountered localized forms of human brucellosis. It is a destructive disease process requiring a correct and early diagnosis and an immediate treatment. Spinal brucellosis is more prevalent in older patients or in subjects with prolonged illness prior to treatment. The lumbar vertebrae are involved more frequently than the thoracic and cervical ones. Paravertebral, epidural, and psoas abscess can occur in the setting of brucellar spondylitis. Medical treatment for brucellar spondylitis should consist of two antibiotic agents for at least 12 weeks.

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Abbreviations

CRP:

C-reactive protein

CT:

Computed tomography

ELISA:

Immunocapture enzyme-linked immunosorbent assay

ESR:

Erythrocyte sedimentation rate

HNP:

Herniated nucleus pulposus

MRI:

Magnetic resonance imaging

PET:

Positron emission tomography

SUVmax:

Maximum standardized uptake value

TMP/SMX:

Trimethoprim/sulfamethoxazole

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Author information

Authors and Affiliations

  1. Department of Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran

    Mitra Ranjbar MD

  2. Department of Radiology, Hacettepe University School of Medicine, Ankara, Turkey

    Ahmet Tuncay Turgut MD

  3. Department of Community Medicine, Iran University of Medical Sciences, Tehran, Iran

    Marzieh Nojomi MD, MPH

  4. Department of Neurosurgery, Adnan Menderes University School of Medicine, Aydın, Turkey

    Mehmet Turgut MD, PhD

Authors
  1. Mitra Ranjbar MD
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  2. Ahmet Tuncay Turgut MD
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  3. Marzieh Nojomi MD, MPH
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  4. Mehmet Turgut MD, PhD
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Corresponding author

Correspondence to Mitra Ranjbar MD .

Editor information

Editors and Affiliations

  1. Department of Neurosurgery, Adnan Menderes University School of Medicine, Aydin, Turkey

    Mehmet Turgut

  2. Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon

    Fuad Sami Haddad

  3. School of Medicine and Surgery, University of Naples Federico II School of Medicine and Surgery, Naples, Italy

    Oreste de Divitiis

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Ranjbar, M., Turgut, A.T., Nojomi, M., Turgut, M. (2016). Brucellar Spondylitis as a Complication of Brucellosis. In: Turgut, M., Haddad, F., de Divitiis, O. (eds) Neurobrucellosis. Springer, Cham. https://doi.org/10.1007/978-3-319-24639-0_12

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  • DOI: https://doi.org/10.1007/978-3-319-24639-0_12

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-24637-6

  • Online ISBN: 978-3-319-24639-0

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