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Directional Fluorescence Based on Surface Plasmon-Coupling

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Reviews in Fluorescence 2015

Part of the book series: Reviews in Fluorescence ((RFLU,volume 8))

Abstract

Fluorescence technology, including the optical sensing and microscopic imaging, has been playing important roles in biology research and medical diagnosis. However it still remains a great challenge to meet the increasing needs of sensitivity and applicability. Surface plasmon-coupled emission (SPCE) is a novel technique that can significantly improve the ability of fluorescence technology. In SPCE, the excited fluorophores will couple with surface plasmons on a continuous thin metal film, which in turn radiate into the higher refractive index media with a narrow angular distribution. Attributed to the direction emission, the sensitivity can be highly improved with the high collection efficiency. This review will summarize the unique features of SPCE that are important in analytical researches, in particular, with a focus on the recent advancements in the strategies for improving the SPCE performance. The optical imaging based on SPCE and some examples of the analytical applications of SPCE are also highlighted. Recent achievements in SPCE suggest that it could provide new technical platforms with widespread potential applications in various areas, such as nucleic acid, protein and other biochemical sensing.

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Acknowledgements

We would like to acknowledge the fund supports from the NSFC (21375111, 21127005, 20975084), the 973 Program of China (2013CB933703, 2007CB935600) and the Ministry of Education of China (20110121110011, PCSIRTIRT13036). We thank Dr. Yu-Luan Chen for critical reading of this manuscript.

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Authors and Affiliations

  1. Department of Chemistry and the MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, China

    Yao-Qun Li, Shuo-Hui Cao, Wei-Peng Cai, Qian Liu, Xiao-Qing Liu & Yu-Hua Weng

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  1. Yao-Qun Li
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  2. Shuo-Hui Cao
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Correspondence to Yao-Qun Li .

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  1. Institute of Fluorescence, University of Maryland Baltimore County Institute of Fluorescence, BALTIMORE, Maryland, USA

    Chris D. Geddes

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Li, YQ., Cao, SH., Cai, WP., Liu, Q., Liu, XQ., Weng, YH. (2016). Directional Fluorescence Based on Surface Plasmon-Coupling. In: Geddes, C. (eds) Reviews in Fluorescence 2015. Reviews in Fluorescence, vol 8. Springer, Cham. https://doi.org/10.1007/978-3-319-24609-3_3

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