Immunology of Keratoplasty

  • Daniel BöhringerEmail author
  • Thomas Reinhard


This is an overview of the current understanding of the pathomechanisms in graft rejection after keratoplasty. We discuss the experimental data on allorecognition and ACAID. We cover tissue typing of the human leukocyte antigen system and selected minor antigens. We give an overview of the clinical evidence in this field. The chapter ends with a recommendation on the best clinical practices with respect to tissue typing in keratoplasty.


ACAID Immune reaction Allorecognition HLA MHC Matching HLAMatchmaker Antibody Minor antigens Histocompatibility 


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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Eye CenterUniversity Hospital FreiburgFreiburgGermany

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