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Novel Use of Existing Imaging Modalities to Assess Intraocular Inflammation

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Multimodal Imaging in Uveitis

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Abstract

The use of imaging for diagnostic or monitoring purposes may be thought of as a pathway from the imaging device to the operational decision-making made by the clinician and patient together. Advances in any part of this process can lead to better visualization or more accurate image interpretation with direct benefit on patient treatment decisions. Much of the rest of this book rightly focuses on the remarkable progress that has been made in the invention of new devices and the improvement in older devices. In this chapter, we consider some of the areas in which established devices are being used in innovative ways to assess intraocular inflammation and set this in the context of the urgent need for objective quantitative measures of intraocular inflammation.

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Abbreviations

AC:

Anterior chamber

ARN:

Acute retinal necrosis

CME:

Cystoid macular edema

CMT:

Central macular thickness

CRVO:

Central retinal vein occlusion

EMEDOCT:

Extramacular enhanced depth optical coherence tomography

ETDRS:

Early Treatment Diabetic Retinopathy Study

FA:

Fluorescein angiography

MUST:

Multicenter Uveitis Steroid Treatment Trial

OCT:

Optical coherence tomography

RNFL:

Retinal nerve fiber layer

SLO:

Scanning laser ophthalmoscopy

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Disclosure

Dr. Keane has received a proportion of his funding from the Department of Health’s NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and UCL Institute of Ophthalmology. The views expressed in the publication are those of the author and not necessarily those of the Department of Health.

Dr. Keane has received travel grants from the Allergan European Retina Panel and given educational presentations for Topcon, Heidelberg, Novartis, Bayer, and Allergan.

Author information

Authors and Affiliations

  1. Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK

    Alastair K. Denniston PhD, FRCOphth

  2. Institute for Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, UK

    Alastair K. Denniston PhD, FRCOphth

  3. NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK

    Alastair K. Denniston PhD, FRCOphth & Pearse A. Keane MD, FRCOphth

Authors
  1. Alastair K. Denniston PhD, FRCOphth
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  2. Pearse A. Keane MD, FRCOphth
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Correspondence to Alastair K. Denniston PhD, FRCOphth .

Editor information

Editors and Affiliations

  1. National Eye Institute National Institutes of Health, Bethesda, Maryland, USA

    H. Nida Sen

  2. Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama, USA

    Russell W. Read

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Denniston, A.K., Keane, P.A. (2018). Novel Use of Existing Imaging Modalities to Assess Intraocular Inflammation. In: Sen, H., Read, R. (eds) Multimodal Imaging in Uveitis. Springer, Cham. https://doi.org/10.1007/978-3-319-23690-2_12

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  • DOI: https://doi.org/10.1007/978-3-319-23690-2_12

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  • Publisher Name: Springer, Cham

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