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Laser-Plasma Particle Sources for Biology and Medicine

  • Antonio GiuliettiEmail author
  • Giancarlo Bussolino
  • Lorenzo Fulgentini
  • Petra Koester
  • Luca Labate
  • Leonida A. Gizzi
Chapter
Part of the Springer Series in Chemical Physics book series (CHEMICAL, volume 112)

Abstract

Ultrashort, intense laser pulses can drive in plasmas small sized linear accelerators (Laser-Linac’s) of high energy elementary particles. These novel devices are facing a continuous, fast progress making them suitable alternatives to conventional linacs in many applications. Among them, cancer therapy may have by far the highest social impact at a global level. This paper is aimed at giving an updated overview of the scientific and technological effort devoted worldwide to the optimization of the laser acceleration technology in order to fulfill the clinical requirements. Here we discuss both ion and electron acceleration considering the different, challenging problems to be solved in each case. Current studies on radiobiology already in progress in many labs with the existing laser-based sources of particles are also described. The overall scenario in the field appears extremely exciting, and promises rapid, effective development.

Keywords

Linear Energy Transfer Amplify Spontaneous Emission Relative Biological Effectiveness Electron Bunch Accelerate Particle 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

The authors of this Chapter are operating in the framework of the CNR High Field Photonics Unit (MD.P03.034). They acknowledge financial support from the CNR funded Italian research Network ‘ELI-Italy (Attoseconds)’, from the Italian Ministry of Health funded project GR-2009-1608935 (D.I. AgeNaS) and from the INFN funded “G-RESIST” project.

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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Antonio Giulietti
    • 1
    Email author
  • Giancarlo Bussolino
    • 1
  • Lorenzo Fulgentini
    • 1
  • Petra Koester
    • 1
  • Luca Labate
    • 1
    • 2
  • Leonida A. Gizzi
    • 1
    • 2
  1. 1.Intense Laser Irradiation LaboratoryIstituto Nazionale di OtticaPisaItaly
  2. 2.INFNSezione di PisaItaly

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