Abstract
Ophthalmologists treating patients with ocular inflammatory diseases are faced with a number of disorders of unknown etiology including, Behçet disease, sarcoidosis, Vogt-Koyanagi-Harada disease, HLA-B27-associated anterior uveitis, Fuchs uveitis syndrome, serpiginous and serpiginoid choroiditis, birdshot chorioretinopathy, and white dot syndromes. Recent data have shown various clues to the role of environmental factors, most importantly, bacteria, viruses, and other pathogens as well as vaccines in the pathogenesis of immune-mediated inflammatory disorders in general and immune-mediated uveitis in particular. Therefore, infectious triggers are increasingly recognized in the etiopathogenesis of various uveitis entities in genetically susceptible individuals. In this chapter we review the role of environmental factors, especially microorganisms, in the pathogenesis of different uveitis entities.
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Oray, M., Tugal-Tutkun, I. (2017). The Role of Infectious Agents in the Pathogenesis of Autoimmune Diseases. In: Chee, SP., Khairallah, M. (eds) Emerging Infectious Uveitis. Springer, Cham. https://doi.org/10.1007/978-3-319-23416-8_2
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