Abstract
Hemodiafiltration has been identified by Fresenius Medical Care (FMC) as a vital need to improve care and outcome of chronic kidney disease patients. By enhancing the removal of middle molecular uremic toxins and improving hemodynamic and global tolerance of dialysis sessions, HDF was recognized as an efficient dialysis modality and a mean to improve patient treatment perception and reduce disease burden. By providing fluid substitution online, HDF appeared the only economically and technically long-term viable solution. Online HDF therapy has been a major R&D focus for FMC over the last decades leading to the development of several online HDF machines with different features.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Canaud B, N’Guyen QV, Lagarde C, et al. Clinical evaluation of a multipurpose dialysis system adequate for hemodialysis or for postdilution hemofiltration/hemodiafiltration with on-line preparation of substitution fluid from dialysate. Contrib Nephrol. 1985;46:184–6.
Roy T. Technical and microbiological safety of online hemodiafiltration: a European perspective. Semin Dial. 1999;12:81–7.
Operating Instructions Fresenius MT 2008 ON-LINE-HDF 2/05.91 (OP), Operating Instructions Fresenius MT 4008 ON-LINE-HDF(4008) 1/12.93 (GA), Operating Instructions Fresenius Medical Care 4008 Onlineplus 5/12.98 (OP), Operating Instructions Fresenius Medical Care 5008 (OP) 3/08.05.
Operating Instructions Fresenius Medical Care 5008 (OP-EN) 10/08.13.
Potier J, Le Roy F, Faucon JP, et al. Elevated removal of middle molecules without significant albumin loss with mixed-dilution hemodiafiltration for patients unable to provide sufficient blood flow rates. Blood Purif. 2013;36:78–83.
Marcelli D, Scholz C, Ponce P, et al. High-volume postdilution hemodiafiltration is a feasible option in routine clinical practice. Artif Organs. 2015;39:142–9.
Maduell F, RodrÃguez N, Sahdalá L, et al. Impact of the 5008 monitor software update on total convective volume. Nefrologia. 2014;34:599–604.
Pedrini LA, De Cristofaro V, Pagliari B, Samà F. Mixed predilution and postdilution online hemodiafiltration compared with the traditional infusion modes. Kidney Int. 2000;58:2155–65.
Ahrenholz PG, Winkler RE, Michelsen A, et al. Dialysis membrane-dependent removal of middle molecules during hemodiafiltration: the beta2-microglobulin/albumin relationship. Clin Nephrol. 2004;6:21–8.
Maduell F, Arias-Guillen M, Fontsere N, et al. Elimination of large uremic toxins by a dialyzer specifically designed for high-volume convective therapies. Blood Purif. 2014;37:125–30.
The new 5008 Cordiax F00005533 GB (BG 08.13) © Copyright 2013 Fresenius Medical Care Deutschland GmbH.
Gross M, Maierhofer A, Tetta C, et al. Online clearance measurement in high-efficiency hemodiafiltration. Kidney Int. 2007;72:1550–3.
Schneditz D, Levin NW. Non-invasive blood volume monitoring during hemodialysis: technical and physiological aspects. Semin Dial. 1997;10:166–9.
Oates T, Cross J, Davenport A. Cost comparison of online haemodiafiltration with high-flux haemodialysis. J Nephrol. 2012;25:192–7.
Lebourg L, Amato S, Toledano D, et al. Online hemodiafiltration: is it really more expensive? Nephrol Ther. 2013;9:209–14.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Canaud, B., Kopperschmidt, P., Spickermann, R., Gatti, E. (2016). Online Hemodiafiltration by Fresenius Medical Care. In: Nubé, M., Grooteman, M., Blankestijn, P. (eds) Hemodiafiltration. Springer, Cham. https://doi.org/10.1007/978-3-319-23332-1_8
Download citation
DOI: https://doi.org/10.1007/978-3-319-23332-1_8
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-23331-4
Online ISBN: 978-3-319-23332-1
eBook Packages: MedicineMedicine (R0)