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Are There Any Disadvantages of Hemodiafiltration?

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Hemodiafiltration

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Abstract

Online postdilution hemodiafiltration (HDF) has been related to an improved patient survival as compared to HD, especially when high convection volumes are applied. Apart from this favorable result, however, online-HDF may evoke side effects that may counteract part of its benefits. Moreover, specific draw backs, related to the set up and maintenance phases of HDF treatment, may hinder the implementation of online HDF on a large scale. So, what are the disadvantages when performing HDF in every day clinical practice? From a medical perspective these may include safety concerns related to the large amounts of substitution fluids directly infused into the patients, the unintended removal of nutrients and other useful compounds including medication, and activation of blood cells. From a financial perspective additional costs may be of relevance. From a practical perspective the main downside of HDF is that starting up a HDF program needs extra efforts of the dialysis staff. In this chapter we discuss the above mentioned issues.

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Author information

Authors and Affiliations

  1. Department of Nephrology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, 3584 CX, The Netherlands

    Peter J. Blankestijn MD

  2. Division of Nephrology, Department of Internal Medicine, University Hospital Maastricht, 5800, Maastricht, Limburg, 6202AZ, The Netherlands

    Jeroen P. Kooman MD, PhD

Authors
  1. Peter J. Blankestijn MD
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  2. Jeroen P. Kooman MD, PhD
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Correspondence to Peter J. Blankestijn MD .

Editor information

Editors and Affiliations

  1. Department of Nephrology, VU University Medical Centre, Amsterdam, The Netherlands

    Menso J. Nubé

  2. Department of Nephrology, VU University Medical Center, Amsterdam, The Netherlands

    Muriel P.C. Grooteman

  3. Department of Nephrology, University Medical Center Utrecht, Utrecht, The Netherlands

    Peter J. Blankestijn

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© 2016 Springer International Publishing Switzerland

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Blankestijn, P.J., Kooman, J.P. (2016). Are There Any Disadvantages of Hemodiafiltration?. In: Nubé, M., Grooteman, M., Blankestijn, P. (eds) Hemodiafiltration. Springer, Cham. https://doi.org/10.1007/978-3-319-23332-1_22

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  • DOI: https://doi.org/10.1007/978-3-319-23332-1_22

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-23331-4

  • Online ISBN: 978-3-319-23332-1

  • eBook Packages: MedicineMedicine (R0)

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