Entraining and Copying of Temporal Correlations in Dissociated Cultured Neurons

  • Terri Roberts
  • Kevin Staras
  • Philip Husbands
  • Andrew Philippides
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 9222)

Abstract

Here we used multi-electrode array technology to examine the encoding of temporal information in dissociated hippocampal networks. We demonstrate that two connected populations of neurons can be trained to encode a defined time interval, and this memory trace persists for several hours. We also investigate whether the spontaneous firing activity of a trained network, can act as a template for copying the encoded time interval to a naïve network. Such findings are of general significance for understanding fundamental principles of information storage and replication.

Keywords

Temporally correlated activity Microelectrode array Neural network Dissociated cultured neurons 

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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Terri Roberts
    • 1
  • Kevin Staras
    • 1
  • Philip Husbands
    • 2
  • Andrew Philippides
    • 2
  1. 1.School of Life SciencesUniversity of SussexBrightonUK
  2. 2.Centre for Computational Neuroscience and Robotics, Department of InformaticsUniversity of SussexBrightonUK

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