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Operative Principles in Managing Patients with Borderline Resectable Pancreas Cancer

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Book cover Multimodality Management of Borderline Resectable Pancreatic Cancer

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Abstract

Borderline resectable pancreas cancer is a complex and challenging disease entity that requires a multidisciplinary team for successful management. The role of the surgeon is to determine the appropriateness and optimal timing of surgical resection, and when feasible, to perform a margin-negative resection and regional lymphadenectomy with minimal morbidity. This chapter discusses considerations regarding the timing of surgery, the basic principles of distal pancreatectomy and pancreaticoduodenectomy for pancreatic adenocarcinoma, and variations in surgical technique and perioperative care that have been investigated prospectively with the aim of minimizing morbidity.

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Abbreviations

BRPC:

Borderline resectable pancreas cancer

CA 19-9:

Carbohydrate antigen 19-9

CR-PF:

Clinically relevant pancreatic fistula

DGE:

Delayed gastric emptying

DP:

Distal pancreatectomy

GDA:

Gastroduodenal artery

JP:

Jackson-Pratt

PD:

Pancreaticoduodenectomy

PF:

Pancreatic fistula

PG:

Pancreaticogastrostomy

PJ:

Pancreaticojejunostomy

PPH:

Post-pancreatectomy hemorrhage

PPPD:

Pylorus-preserving pancreaticoduode-nectomy

RAMPS:

Radical antegrade modular pancreato-splenectomy

SL:

Staging laparoscopy

SMA:

Superior mesenteric artery

SMV:

Superior mesenteric vein

TP:

Total pancreatectomy

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Author information

Authors and Affiliations

  1. Department of Surgery, University of California San Diego, Moores Cancer Center, 3855 Health Sciences Drive, Mail Code 0987, La Jolla, CA, 92011, USA

    Kaitlyn J. Kelly M.D.

  2. Department of Surgical Oncology, Unviersity of California San Diego, 3855 Health Center Drive, Mail Code 0987, La Jolla, CA, 92093, USA

    Andrew M. Lowy

Authors
  1. Kaitlyn J. Kelly M.D.
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Corresponding author

Correspondence to Kaitlyn J. Kelly M.D. .

Editor information

Editors and Affiliations

  1. Department of Surgical Oncology, MD Anderson Cancer Center, Houston, Texas, USA

    Matthew H.G. Katz

  2. Division of Surgical Oncology, The University of Cincinnati Medical Center, Cincinnati, Ohio, USA

    Syed A. Ahmad

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Kelly, K.J., Lowy, A.M. (2016). Operative Principles in Managing Patients with Borderline Resectable Pancreas Cancer. In: Katz, M., Ahmad, S. (eds) Multimodality Management of Borderline Resectable Pancreatic Cancer. Springer, Cham. https://doi.org/10.1007/978-3-319-22780-1_11

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  • DOI: https://doi.org/10.1007/978-3-319-22780-1_11

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-22779-5

  • Online ISBN: 978-3-319-22780-1

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