Abstract
Considerations elaborated on in this volume support the concept that the malignantly transformed cell is driven by an ancient, but well conserved substance of the RNA/DNA complex. In the pre-cellular world, RNA was the progenitor of the first DNA molecules. The one-exon Sox2 sequence remains preserved embedded in a long noncoding ncRNA strand in the human genome at 3q26.3-q27, as a relic of their ancient biophysical precellular relationship. The primordial RNA/DNA complex remains preserved in the archaea, and in the cells of unicellular, early multicellular, or advanced multicellular eukaryotic hosts as chloroplasts and mitochondria.
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© 2016 Springer International Publishing Switzerland
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Sinkovics, J.G. (2016). Summary. In: RNA/DNA and Cancer. Springer, Cham. https://doi.org/10.1007/978-3-319-22279-0_30
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DOI: https://doi.org/10.1007/978-3-319-22279-0_30
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