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Perioperative Care of the Pediatric Neurosurgical Patient

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Perioperative Medicine in Pediatric Anesthesia
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Abstract

Age-related differences have to be considered when a child is scheduled for a neurosurgical procedure. Differences in neurophysiology of the developing human brain influence the approach to these patients. The anesthesiologist should pay attention to age-specific symptoms and signs of raised intracranial pressure during preanesthesia assessment. Anesthesia induction and maintenance should be targeted to an adequate age-related perfusion pressure to avoid cerebral ischemia. Main complications could be related to intraoperative blood losses, postoperative metabolic disorders, and seizures. New development in pediatric neurosurgery and critical care allowed improving outcomes of children with neurological and neurosurgical problems. At the same time, specific pediatric neuroanesthesia training should be assured for better management of infants and small children.

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References

  1. Chiron C, Raynaud C, Maziere B et al (1992) Changes in regional cerebral blood flow during brain maturation in children and adolescents. J Nucl Med 33:696–703

    CAS  PubMed  Google Scholar 

  2. Mackersie A (1999) Paediatric neuroanaesthesia. Balliere’s Clin Anaesthesiol 13:593–604

    Google Scholar 

  3. Feinendegen LE, Herzog H, Thompson KH (2001) Cerebral glucose transport implies individualized glial cell function. J Cereb Blood Flow Metab 21:1160–1170

    Article  CAS  PubMed  Google Scholar 

  4. Weir CJ, Murray GD, Dyker AG et al (1997) Is hyperglycaemia an independent predictor of poor outcome after acute stroke? Results of a long-term follow up study. BMJ 314:1303–1306

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  5. Curley G, Kavanagh BP, Laffey JG (2011) Hypocapnia and the injured brain: evidence for harm. Crit Care Med 39:229–230

    Article  PubMed  Google Scholar 

  6. Krane EJ, Phillip BM, Yeh KK, Domino KB (1986) Anaesthesia for paediatric neurosurgery. In: Smith RM, Mototyama EK, Davis PJ (eds) Smith’s anaesthesia for infants and children, vol 2006, 7th edn. Mosby, Philadelphia, pp 651–684

    Google Scholar 

  7. Munro MJ, Walker AM, Barfield CP (2004) Hypotensive extremely low birth weight infants have reduced cerebral blood flow. Pediatrics 114:1591–1596

    Article  PubMed  Google Scholar 

  8. Tyszczuk L, Meek J, Elwell C et al (1998) Cerebral blood flow is independent of mean arterial blood pressure in preterm infants undergoing intensive care. Pediatrics 102:337–341

    Article  CAS  PubMed  Google Scholar 

  9. Vavilala MS, Lee LA, Lam AM (2003) The lower limit of cerebral autoregulation in children during sevoflurane anesthesia. J Neurosurg Anesthesiol 15:307–312

    Article  PubMed  Google Scholar 

  10. Torvik A (1984) The pathogenesis of watershed infarcts in the brain. Stroke 15:221–223

    Article  CAS  PubMed  Google Scholar 

  11. Whalen MJ, Carlos TM, Kochanek PM et al (2000) Interleukin-8 is increased in cerebrospinal fluid of children with severe head injury. Crit Care Med 28:929–934

    Article  CAS  PubMed  Google Scholar 

  12. Chyatte D, Bruno G, Desai S et al (1999) Inflammation and intracranial aneurysms. Neurosurgery 45:1137–1146; discussion 1146–1147

    Article  CAS  PubMed  Google Scholar 

  13. Bracco D, Ravussin P (2000) Neuroinflammation and infection. Curr Opin Anaesthesiol 13:523–528

    Article  CAS  PubMed  Google Scholar 

  14. Blume WT (1982) Atlas of pediatric encephalography. Raven, New York

    Google Scholar 

  15. Holmes GL (1989) Diagnosis and management of seizures in children. W.B. Saunders Company, Philadelphia

    Google Scholar 

  16. Petersen I, Eeg-Olofsson O (1971) The development of the electroencephalogram in normal children from the age of 1 through 15 years. Neuropadiatrie 2:247–304

    Article  CAS  PubMed  Google Scholar 

  17. Novotny EJ (1998) The role of clinical neurophysiology in the management of epilepsy. J Clin Neurophysiol 15(2):98–108

    Article  Google Scholar 

  18. Stratmann G (2011) Review article: neurotoxicity of anesthetic drugs in the developing brain. Anesth Analg 113:1170–1179

    Article  CAS  PubMed  Google Scholar 

  19. Pruett D, Waterman EH, Caughey AB (2013) Fetal alcohol exposure: consequences, diagnosis, and treatment. Obstet Gynecol Surv 68:62–69

    Article  PubMed  Google Scholar 

  20. Ikonomidou C, Bittigau P, Ishimaru MJ et al (2000) Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome. Science 287:1056–1060

    Article  CAS  PubMed  Google Scholar 

  21. Jevtovic-Todorovic V, Hartman RE, Izumi Y et al (2003) Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits. J Neurosci 23:876–882

    CAS  PubMed  Google Scholar 

  22. Brambrink AM, Back SA, Riddle A (2012) Isoflurane-induced apoptosis of oligodendrocytes in the neonatal primate brain. Ann Neurol 72:525–535

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  23. Brambrink AM, Evers AS, Avidan MS (2012) Ketamine-induced neuroapoptosis in the fetal and neonatal rhesus macaque brain. Anesthesiology 116:372–384

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  24. Brambrink AM, Evers AS, Avidan MS (2010) Isoflurane-induced neuroapoptosis in the neonatal rhesus macaque brain. Anesthesiology 112:834–841

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  25. Flick RP, Katusic SK, Colligan RC (2011) Cognitive and behavioral outcomes after early exposure to anesthesia and surgery. Pediatrics 128:e1053–e1061

    Article  PubMed Central  PubMed  Google Scholar 

  26. Hansen TG, Pedersen JK, Henneberg SW (2011) Academic performance in adolescence after inguinal hernia repair in infancy: a nationwide cohort study. Anesthesiology 114:1076–1085

    Article  PubMed  Google Scholar 

  27. Ing C, DiMaggio C, Whitehouse A (2012) Long-term differences in language and cognitive function after childhood exposure to anesthesia. Pediatrics 130:e476–e485

    Article  PubMed  Google Scholar 

  28. Walker K, Halliday R, Holland AJ (2010) Early developmental outcome of infants with infantile hypertrophic pyloric stenosis. J Pediatr Surg 45:2369–2372

    Article  PubMed  Google Scholar 

  29. Cohen MM, Cameron CB, Duncan PG (1990) Pediatric anesthesia morbidity and mortality in the perioperative period. Anesth Analg 70:160–167

    Article  CAS  PubMed  Google Scholar 

  30. Faraoni D, Goobie SM (2014) The efficacy of antifibrinolytic drugs in children undergoing noncardiac surgery: a systematic review of the literature. Anesth Analg 118:628–636

    Article  CAS  PubMed  Google Scholar 

  31. Mekitarian Filho E, Carvalho WB, Cavalheiro S, Horigoshi NK, Freddi NA (2011) Hyperglycemia and postoperative outcomes in pediatric neurosurgery. Clinics 66:1637–1640

    Article  PubMed  Google Scholar 

  32. Barker F II (2007) Efficacy of prophylactic antibiotics against meningitis after craniotomy: a meta-analysis. Neurosurgery 60:887–894

    Article  PubMed  Google Scholar 

  33. Tremon-Lukats IW, Ratilal BO, Armstrong T, Gilbert MR (2008) Antiepileptic drugs for preventing seizures in people with brain tumors. Cochrane Database Syst Rev (2):CD004424

    Google Scholar 

  34. Soriano SG, Eldredge EA, Wang FK et al (2000) The effect of propofol on intraoperative electrocorticography and cortical stimulation during awake craniotomies in children. Paediatr Anaesth 10:29–34

    Article  CAS  PubMed  Google Scholar 

  35. Beier AD, Rutka JT (2013) Hemispherectomy: historical review and recent technical advances. Neurosurg Focus 34:E11

    Article  PubMed  Google Scholar 

  36. Flack S, Ojemann J, Haberkern C (2008) Cerebral hemispherectomy in infants and young children. Paediatr Anaesth 18:967–973

    Article  PubMed  Google Scholar 

  37. Sethna NF, Zurakowski D, Brustowicz RM et al (2005) Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery. Anesthesiology 102:727–732

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Massimo Lamperti MD .

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Lamperti, M. (2016). Perioperative Care of the Pediatric Neurosurgical Patient. In: Astuto, M., Ingelmo, P. (eds) Perioperative Medicine in Pediatric Anesthesia. Anesthesia, Intensive Care and Pain in Neonates and Children. Springer, Cham. https://doi.org/10.1007/978-3-319-21960-8_8

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  • DOI: https://doi.org/10.1007/978-3-319-21960-8_8

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-21959-2

  • Online ISBN: 978-3-319-21960-8

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