Abstract
This work presents an electro-mechanical model of the cardiac tissue and an automatic way to tune its parameters. A cellular automaton was used to simulate the action potential propagation, and a mass-spring system to model the tissue contraction. A parallel genetic algorithm was implemented in order to automatically adjust a simple and fast discrete model, to reproduce simulations of another synthetic well known model based on differential equations (DEs). Our results suggest that the discrete model was able to qualitatively reproduce the results obtained by DEs with much less computational effort.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Gharpure, P.B.: A cellular automaton model of electrical wave propagation in cardiac muscle. Ph.D. thesis, Department of Bioengineering, The University of Utah (1996)
Bora, C., Serinagaoglu, Y., Tonuk, E.: Electromechanical heart tissue model using cellular automaton. In: Biomedical Engineering Meeting (BIYOMUT) 1–4 (2010)
Gharpure, P.B., Johnson Christopher, R. Harrison, N.E.: A cellular automaton model of electrical activation in canine ventricles: A validation study. Annal. Biomed. Eng, n. pag (1995)
Campos, R.S., Lobosco, M., dos Santos, R.W.: A GPU-based heart simulator with mass-spring systems and cellular automaton. J. Supercomputing 69, 1–8 (2014)
Bourguignon, D., Cani, M.P.: Controlling Anisotropy in Mass-Spring Systems. In: Magnenat-Thalmann, N., Thalmann, D., Arnaldi, B. (eds.) Computer Animation and Simulation 2000, pp. 113–123. Springer, Vienna (2000)
Oussama Jarrouse: Modified Mass-Spring System for Physically Based Deformation Modeling. Ph.D. thesis, Karlsruher Instituts fur Technologie (2011)
Vinnakota, K.C., Bassingthwaighte, J.B.: Myocardial density and composition: a basis for calculating intracellular metabolite concentrations. Am. J. Physiol. - Heart Circulatory Physiol. 286, H1742–H1749 (2004)
Nobile, F., Quarteroni, A., Ruiz-Baier, R.: An active strain electromechanical model for cardiac tissue. Int. J. Numer. Methods Biomed. Eng. 28, 52–71 (2012)
Holzapfel, G.A., Ogden, R.W.: Constitutive modelling of passive myocardium: a structurally based framework for material characterization. Philos. Trans. Roy. Soc. A 367, 3445–3475 (2009)
de Oliveira, B.L., Rocha, B.M., Toledo, E.M., Barra, L.P.S., Sundnes, J., dos Santos, R.W.: Effects of deformation on transmural dispersion of repolarization using in silico models of human left ventricular wedge. Int. J. Numer. Methods Biomed. Eng. 29, 1323–1337 (2013)
Acknowledgments
The authors thank CAPES, CNPq, FAPEMIG and UFJF for supporting this work.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer International Publishing Switzerland
About this paper
Cite this paper
Campos, R.S., Rocha, B.M., da Silva Barra, L.P., Lobosco, M., dos Santos, R.W. (2015). A Parallel Genetic Algorithm to Adjust a Cardiac Model Based on Cellular Automaton and Mass-Spring Systems. In: Malyshkin, V. (eds) Parallel Computing Technologies. PaCT 2015. Lecture Notes in Computer Science(), vol 9251. Springer, Cham. https://doi.org/10.1007/978-3-319-21909-7_15
Download citation
DOI: https://doi.org/10.1007/978-3-319-21909-7_15
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-21908-0
Online ISBN: 978-3-319-21909-7
eBook Packages: Computer ScienceComputer Science (R0)