Creation of Definitions for Ontologies: A Case Study in the Leukemia Domain

  • Amanda Damasceno de SouzaEmail author
  • Maurício Barcellos Almeida
  • Joaquim Caetano de Aguirre Neto
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 9162)


The creation of the definitions it is an important stage of the activity of ontologies construction, insofar as the definitions provides the understanding of the meaning of classes. However, creating definitions is a complex and tiresome task. This study is part of an ongoing research that analyses some fundamental principles with the aim of formulating textual and formal definitions to be used in ontologies. The context of such analysis is a project of knowledge organization within the biomedical domain. The goal is to establish methodological guidelines for formulating the definitions in biomedical ontologies. In general, people building ontologies do not make use of consistent rules for the correct formulation of definitions, which, we believe, make our study a relevant initiative. As partial results, we present a list of topics that corresponds to the aforementioned methodological guidelines.


Definitions Biomedical ontologies Leukemia 


  1. 1.
    Spear A.D.: Ontology for the Twenty First Century: An Introduction with Recommendations. Institute for Formal Ontology and Medical Information Science (IFOMIS), Saarbrücken, Germany. University at Buffalo, New York. (2006).
  2. 2.
    Washington, N., Lewis, S.: Ontologies: Scientific Data Sharing Made Easy. Nat. Educ. 1(3), 5 (2008)Google Scholar
  3. 3.
    Almeida, M.B., Barbosa, R.R.: Ontologies in knowledge management support - a case study. J Am Soc. Inf. Sci. Technol. 60(10), 2032–2047 (2009)CrossRefGoogle Scholar
  4. 4.
    Wernig, G., Gilliland, G.: Pathobiology of acute myeloid leukemia. In: Hoffman, R., et al. (eds.) Hematology: Basic Principle and Practice. 5th.ed. Churchill Livingstone, pp. 921–932. Elsevier, Philadelphia (2009)Google Scholar
  5. 5.
    Michael, J., Mejino Jr., J.L., Rosse, C.: The role of definitions in biomedical concept representation.In: Proceedings of the AMIA Symposium, pp. 463–467 (2001)Google Scholar
  6. 6.
    Almeida, M.B., et al. The Blood Ontology: an ontology in the domain of hematology. In: Proceedings of the International Conference of Biomedical Ontologies (2011).
  7. 7.
    Köhler, J., et al.: Quality control for terms and definitions in ontologies and taxonomies. BMC Bioinf. 7, 212 (2006)CrossRefGoogle Scholar
  8. 8.
    Smith, B., et al.: Relations in biomedical ontologies. Genome Biol. 6(5), R46 (2005)CrossRefGoogle Scholar
  9. 9.
    Seppälä, S., Ruttenberg, R.: Survey on defining practices in ontologies: Report in the international workshop on definitions in ontologies. In: ICBO 2013, Montreal, Quebec, Canada (2013).
  10. 10.
    Petrova, A., et al.: Formalizing biomedical concepts from textual definitions. J. Biomed. Semant. 6, 22 (2015)CrossRefGoogle Scholar
  11. 11.
    Seppälä, S., Schreiber, Y., Ruttenberg., A.: Textual and logical definitions in ontologies. In: Proceedings of DIKR 2014, IWOOD 2014, CEUR Workshop Proceedings, Houston, TX, USA, (1309), pp.35–41 (2014).
  12. 12.
    Tsatsaronis, G., et al.: Learning formal definitions for biomedical concepts.In: Srinivas, K, Jupp, S. (eds) Proceedings of the 10th OWL: Experiences and Directions Workshop (OWLED) (2013).
  13. 13.
    Schulz, S., Kumar, A., Bittner, T.: Biomedical ontologies: what part-of is and isn’t. J. Biomed. Inform. 39(3), 350–361 (2006)CrossRefGoogle Scholar
  14. 14.
    Liss, P.E., et al.: Terms used to describe urinary tract infections–the importance of conceptual clarification. APMIS. 111(2), 291–299 (2003)CrossRefzbMATHGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Amanda Damasceno de Souza
    • 1
    Email author
  • Maurício Barcellos Almeida
    • 2
  • Joaquim Caetano de Aguirre Neto
    • 3
  1. 1.School of Information ScienceFederal University of Minas GeraisBelo HorizonteBrazil
  2. 2.Department of Theory and Management of InformationFederal University of Minas GeraisBelo HorizonteBrazil
  3. 3.Centro de Qimioterapia Antiblastica e ImunoterapiaBelo HorizonteBrazil

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