Vaginal cancer is a rare tumor which constitutes only 2 % of female genital tract cancers. There are some known causes such as age, HPV infection, social background, chronic conditions as well as unknown causes. The most common symptoms for vaginal cancer are: vaginal bleeding often postcoital, vaginal discharge, dysuria, pelvic pain and/or pelvic mass. The main volume of the theory regarding the treatment of vaginal cancer is based on radiotherapy and there are reports of surgical methods. Treatment selection factors include the extent of the primary disease (stage), histological type, location of recurrence, extent of the recurring disease, primary therapy, evidence of metastatic disease, performance status (PS), patient age and comorbidities. The reported overall 5-year survival rate for vaginal cancer is 44 %, which is poorer than that for both cervical and vulvar cancer.

In current oncology, survival rate is the primary target, but the analysis of the treatment complications and the quality of life is of crucial importance, particularly in cancers with indolent biology. It is difficult to establish strong, evidence-based recommendations as cancer of the vagina is such a rare disease. However, there are therapeutic options based on understanding the tumor biology and in individual treatment of the patient. Women with vaginal cancer should be managed in a cancer center within a multidisciplinary team (MDT) setting.


Intensity Modulate Radiation Therapy Adenoid Cystic Carcinoma High Grade Squamous Intraepithelial Lesion National Cancer Data Base Invasive Squamous Cell Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer International Publishing Switzerland 2015

Authors and Affiliations

  1. 1.Department of Medical OncologyUniversity of LarissaLarissaGreece

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