The coexistence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA), called the “overlap syndrome” (OS), is associated with an increased morbidity and mortality burden. Although the management of the OSA component is based on positive airway pressure (PAP) therapy, the treatment benefit seems to extend to the COPD part of the syndrome. PAP therapy in overlap syndrome is associated with an improvement in lung function, arterial blood gases, vascular function, COPD exacerbations, mortality, and quality of life.
- Overlap syndrome
- Chronic obstructive pulmonary disease
- Sleep apnea
- Sleep-disordered breathing
- Continuous positive airway pressure
- Noninvasive ventilation
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Conflict of Interest
Supported by a grant from the American Sleep Medicine Foundation (PJ) and a Merit Review Grant (CX000478) from the Department of Veterans Affairs (AES). The views expressed in this review do not communicate an official position of the Department of Veterans Affairs.
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© 2016 Springer International Publishing Switzerland
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Jaoude, P., El Solh, A.A. (2016). Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnea, Known as the Overlap Syndrome: Indications for CPAP and BiPAP. Evidence and Key Practical Recommendations. In: Esquinas, A. (eds) Noninvasive Mechanical Ventilation. Springer, Cham. https://doi.org/10.1007/978-3-319-21653-9_86
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-21652-2
Online ISBN: 978-3-319-21653-9