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Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnea, Known as the Overlap Syndrome: Indications for CPAP and BiPAP. Evidence and Key Practical Recommendations

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Noninvasive Mechanical Ventilation

Abstract

The coexistence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA), called the “overlap syndrome” (OS), is associated with an increased morbidity and mortality burden. Although the management of the OSA component is based on positive airway pressure (PAP) therapy, the treatment benefit seems to extend to the COPD part of the syndrome. PAP therapy in overlap syndrome is associated with an improvement in lung function, arterial blood gases, vascular function, COPD exacerbations, mortality, and quality of life.

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Financial Support

Supported by a grant from the American Sleep Medicine Foundation (PJ) and a Merit Review Grant (CX000478) from the Department of Veterans Affairs (AES). The views expressed in this review do not communicate an official position of the Department of Veterans Affairs.

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Correspondence to Ali A. El Solh MD, MPH .

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Jaoude, P., El Solh, A.A. (2016). Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnea, Known as the Overlap Syndrome: Indications for CPAP and BiPAP. Evidence and Key Practical Recommendations. In: Esquinas, A. (eds) Noninvasive Mechanical Ventilation. Springer, Cham. https://doi.org/10.1007/978-3-319-21653-9_86

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  • DOI: https://doi.org/10.1007/978-3-319-21653-9_86

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-21652-2

  • Online ISBN: 978-3-319-21653-9

  • eBook Packages: MedicineMedicine (R0)

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