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Nasal High Flow: Novel Approach for Ventilatory Assist During Sleep

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Noninvasive Mechanical Ventilation

Abstract

An open nasal cannula system for delivering warm and humidified air or oxygen at higher flow rates (2–50 l/min) has been shown to assist ventilation and outcomes in the acute setting in adults and in children. Nasal high flow (NHF) has been extended to assist ventilation during sleep and to treat sleep-disordered breathing. This chapter reviews the medical and technical requirements needed to use NHF during sleep and NHF’s effect on disordered breathing during sleep. The reason for this review is the promise of NHF becoming an alternative to conventional ventilatory assist such as nocturnal oxygen, positive pressure support, and nocturnal ventilation, all of which are hampered by a low adherence, leaving a majority of patients insufficiently treated.

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Abbreviations

BiPAP:

Bi-level positive airway pressure

COPD:

Chronic obstructive pulmonary disease

CPAP:

Continuous positive airway pressure

ICU:

Intensive care unit

LTOT:

Long-term oxygen therapy

NIV:

Noninvasive mechanical ventilation

OSA:

Obstructive sleep apnea

References

  1. McEvoy RD, Pierce RJ, Hillman D, Esterman A, Ellis EE, Catcheside PG, O’Donoghue FJ, Barnes DJ, Grunstein RR. Nocturnal non-invasive nasal ventilation in stable hypercapnic COPD: a randomised controlled trial. Thorax. 2009;64:561–6.

    Article  CAS  PubMed  Google Scholar 

  2. Lee JH, Rehder KJ, Williford L, Cheifetz IM, Turner DA. Use of high flow nasal cannula in critically ill infants, children, and adults: a critical review of the literature. Intensive Care Med. 2013;39:247–57.

    Article  PubMed  Google Scholar 

  3. Sotello D, Rivas M, Mulkey Z, Nugent K. High-flow nasal cannula oxygen in adult patients: a narrative review. Am J Med Sci. 2015;349:179–85.

    Article  PubMed  Google Scholar 

  4. Mundel T, Feng S, Tatkov S, Schneider H. Mechanisms of nasal high flow on ventilation during wakefulness and sleep. J Appl Physiol. 2013;114:1058–65.

    Article  PubMed Central  PubMed  Google Scholar 

  5. Parke R, McGuinness S, Eccleston M. Nasal high-flow therapy delivers low level positive airway pressure. Br J Anaesth. 2009;103:886–90.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  6. Sowho MO, Woods MJ, Biselli P, McGinley BM, Buenaver LF, Kirkness JP. Nasal insufflation treatment adherence in obstructive sleep apnea. Sleep Breath. 2014;19(1):351–7.

    Article  Google Scholar 

  7. Moller WG, Celik S, Feng P, Bartenstein G, Meyer O, Eickelberg O, Schmid O, Tatkov S. Nasal high flow clears anatomical dead space in upper airway models. J Appl Physiol. 2015. DOI: 10.1152/japplphysiol.00934.2014

    Google Scholar 

  8. Tagaito Y, Schneider H, O’Donnell CP, Smith PL, Schwartz AR. Ventilating with tracheal gas insufflation and periodic tracheal occlusion during sleep and wakefulness. Chest. 2002;122:1742–50.

    Article  CAS  PubMed  Google Scholar 

  9. Schneider H, O’hearn DJ, Leblanc K, Smith PL, O’Donnell CP, Eisele DW, Peter JH, Schwartz AR. High-flow transtracheal insufflation treats obstructive sleep apnea. A pilot study. Am J Respir Crit Care Med. 2000;161:1869–76.

    Article  CAS  PubMed  Google Scholar 

  10. McGinley B, Halbower A, Schwartz AR, Smith PL, Patil SP, Schneider H. Effect of a high-flow open nasal cannula system on obstructive sleep apnea in children. Pediatrics. 2009;124:179–88.

    Article  PubMed Central  PubMed  Google Scholar 

  11. Nilius G, Franke KJ, Domanski U, Ruhle KH, Kirkness JP, Schneider H. Effects of nasal insufflation on arterial gas exchange and breathing pattern in patients with chronic obstructive pulmonary disease and hypercapnic respiratory failure. Adv Exp Med Biol. 2013;755:27–34.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Hartmut Schneider MD PhD .

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© 2016 Springer International Publishing Switzerland

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Schneider, H., Kirkness, J.P. (2016). Nasal High Flow: Novel Approach for Ventilatory Assist During Sleep. In: Esquinas, A. (eds) Noninvasive Mechanical Ventilation. Springer, Cham. https://doi.org/10.1007/978-3-319-21653-9_80

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  • DOI: https://doi.org/10.1007/978-3-319-21653-9_80

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-21652-2

  • Online ISBN: 978-3-319-21653-9

  • eBook Packages: MedicineMedicine (R0)

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