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Dipyridamole Stress Echocardiography

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Stress Echocardiography

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Abstract

Dipyridamole was the first pharmacological stress agent used for the diagnosis of coronary artery disease, with a pioneering indicator proposed in Europe for the identification of ischemia during stress echocardiography [1] and later in the USA by Lance Gould as hyperemic stress perfusion imaging [2]. Its main cardiac imaging applications stem from two fundamental properties, which are the two imaging sides of the same pathophysiological coin of coronary arteriolar vasodilation: the hyperemic effect and the proischemic effect [3]. The hyperemic effect is the conceptual basis for myocardial perfusion imaging, usually with radionuclide scintigraphy but today also with cardiovascular magnetic resonance [4]. The ischemic effect is the requisite for functional imaging, usually with two-dimensional (2D) echocardiography (Fig. 13.1), but today also performed with magnetic resonance [5].

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Authors and Affiliations

  1. Cardiodiagnostico, Investigaciones medicas, Buenos Aires, Argentina

    Jorge Lowenstein MD, FASE

  2. CNR Pisa Ist. Fisiologia Clinica, Via Moruzzi 1, Pisa, 56124, Italy

    Eugenio Picano MD, PhD

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  1. Jorge Lowenstein MD, FASE
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  2. Eugenio Picano MD, PhD
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Table of Contents Video Companion

Table of Contents Video Companion

  • See stress echo primer, cases 1 to 8.

  • See also, in the section illustrative cases, cases number 1 to 8 (by Maria Joao Andrade, MD, Carnaxide, Lisbon, Portugal) and cases 13 to 18 (by Jorge Lowenstein, MD, Buenos Aires, Argentina, and Quirino Ciampi, MD, PhD, Benevento, Italy).

  • See also in the section “Selected presentations: Angels in the stress echo lab.”

  • Springer Extra Materials available at http://extras.springer.com/2015/978-3-319-20957-9

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Lowenstein, J., Picano, E. (2015). Dipyridamole Stress Echocardiography. In: Stress Echocardiography. Springer, Cham. https://doi.org/10.1007/978-3-319-20958-6_13

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