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Musculoskeletal Research and Basic Science pp 269–281Cite as

Stem Cell Therapy and Orthopedics

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Abstract

Stem cells obtained from various sources in the body and during different stages of development form the basis of cellular therapy and are often studied in the field of orthopedic regenerative medicine. Parameters such as potential, source, route of administration, and desired dose of stem cells to be used should be selected according to the type of regeneration, and research and application should be conducted with this in mind. This chapter details the general characteristics of stem cells, sources of stem cells, and the advantages and disadvantages of the various sources of stem cells. Detailed specifications of adult stem cells in the group of mesenchymal stem cells, which have more advantages in the field of orthopedics than other stem cells, are provided. Briefly, induced pluripotent stem cells and tissue engineering studies are discussed and examples of orthopedic studies with stem cells are provided.

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Author information

Authors and Affiliations

  1. Hacettepe University Medical Faculty, Stem Cell Research and Application Center, Sihhiye, Ankara, 06100, Turkey

    Sevil Köse MS & Duygu Uçkan Çetinkaya MD, PhD

  2. International Research Fellow, Knee Surgery & Sports Medicine, Seoul National University Bundang Hospital, ■, Korea

    Gaurav Sharma MD

  3. Professor, Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul, Korea

    Tae Kyun Kim MD, PhD

  4. Director, Knee Surgery & Sports Medicine, Seoul National University Bundang Hospital, ■, Korea

    Tae Kyun Kim MD, PhD

  5. Department of Histology and Embryology, Hacettepe University Medical Faculty, Sihhiye, Ankara, 06100, Turkey

    Petek Korkusuz MD, PhD

  6. Department of Sports Medicine, Hacettepe University Medical Faculty, Sihhiye, Ankara, 06100, Turkey

    Feza Korkusuz MD, PhD

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  1. Sevil Köse MS
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  2. Duygu Uçkan Çetinkaya MD, PhD
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  3. Gaurav Sharma MD
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  4. Tae Kyun Kim MD, PhD
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  5. Petek Korkusuz MD, PhD
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  6. Feza Korkusuz MD, PhD
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Corresponding author

Correspondence to Petek Korkusuz MD, PhD .

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Editors and Affiliations

  1. Department of Sports Medicine, Hacettepe University Medical Faculty, Ankara, Turkey

    Feza Korkusuz

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Köse, S., Çetinkaya, D.U., Sharma, G., Kim, T.K., Korkusuz, P., Korkusuz, F. (2016). Stem Cell Therapy and Orthopedics. In: Korkusuz, F. (eds) Musculoskeletal Research and Basic Science. Springer, Cham. https://doi.org/10.1007/978-3-319-20777-3_15

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  • DOI: https://doi.org/10.1007/978-3-319-20777-3_15

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-20776-6

  • Online ISBN: 978-3-319-20777-3

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