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Loess and Spline Modeling (90 Patients)

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SPSS for Starters and 2nd Levelers

Abstract

Plasma concentration time curves are the basis of pharmacokinetics. If traditional nonlinear models do not fit the data well, spline and loess (locally weighted scatter plot smoothing) modeling will provide a possible solution.

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Cleophas, T.J., Zwinderman, A.H. (2016). Loess and Spline Modeling (90 Patients). In: SPSS for Starters and 2nd Levelers. Springer, Cham. https://doi.org/10.1007/978-3-319-20600-4_26

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