Abstract
Preoperative fasting is a routine that aims to secure an empty stomach by the time of induction of anesthesia in order to reduce the risk of regurgitation of acid gastric content that may flow into the lungs and cause dangerous chemical pneumonia. Based on studies of gastric emptying of various foods and drinks, recent guidelines for elective surgery recommend that while solid food should not be taken within 6 h prior to induction of anesthesia, intake of clear liquids can be recommended to most patients until 2 h before anesthesia. Although this makes perfect sense to any health professional having studied the physiology of gastric emptying and/or fluid absorption and metabolism, this guideline is probably one of the most underused worldwide today. The reason for this is likely to be historic. But it may also relate to the reluctance of the medical community to change habits from traditional ways to evidence-based practice and the ease of sticking to a rule that is simple and well known.
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References
Maltby JRYP. Fasting from midnight—the history behind the dogma. Best Pract Res Clin Anaesthesiol. 2006;20(3):363–78.
Simpson JY. Remarks on the alleged case of death from the action of chloroform. Lancet. 1848;1:175–6.
Lister J. On anaesthestics. In: Holmes T, editor. Holmes system of surgery. London: Lingmans Green and Co.; 1883.
Mendelson C. The aspiration of stomach contents into the lungs during obstetric anaesthesia. Am J Obstet Gynecol. 1946;52:191–205.
Maltby JR, et al. Preoperative oral fluids: is a five-hour fast justified prior to elective surgery? Anesth Analg. 1986;65(11):1112–6.
Olsson GL, Hallen B, Hambraeus-Jonzon K. Aspiration during anaesthesia: a computer-aided study of 185,358 anaesthetics. Acta Anaesthesiol Scand. 1986;30(1):84–92.
Madsen M, Brosnan J, Nagy VT. Perioperative thirst: a patient perspective. J Perianesth Nurs. 1998;13(4):225–8.
Goresky GV, Maltby JR. Fasting guidelines for elective surgical patients. Can J Anaesth. 1990;37(5):493–5.
Soreide E, Fasting S, Raeder J. New preoperative fasting guidelines in Norway. Acta Anaesthesiol Scand. 1997;41(6):799.
Smith I, et al. Perioperative fasting in adults and children: guidelines from the European Society of Anaesthesiology. Eur J Anaesthesiol. 2011;28(8):556–69.
Ljungqvist O. Modulating postoperative insulin resistance by preoperative carbohydrate loading. Best Pract Res Clin Anaesthesiol. 2009;23:401–9.
Ljungqvist O, et al. Glucose infusion instead of preoperative fasting reduces postoperative insulin resistance. J Am Coll Surg. 1994;178(4):329–36.
Crowe PJ, Dennison A, Royle GT. The effect of pre-operative glucose loading on postoperative nitrogen metabolism. Br J Surg. 1984;71(8):635–7.
Nygren J, et al. Preoperative gastric emptying. Effects of anxiety and oral carbohydrate administration. Ann Surg. 1995;222(6):728–34.
Witasp A, et al. Increased expression of inflammatory pathway genes in skeletal muscle during surgery. Clin Nutr. 2009;28(3):291–8.
Gjessing PF et al. Preoperative carbohydrate supplementation attenuates post-surgery insulin resistance via reduced inflammatory inhibition of the insulin-mediated restraint on muscle pyruvate dehydrogenase kinase 4 expression. Clin Nutr. 2014 Dec 11. pii: S0261-5614(14)00302-1.
Thorell A, Nygren J, Ljungqvist O. Insulin resistance: a marker of surgical stress. Curr Opin Clin Nutr Metab Care. 1999;2(1):69–78.
Sato H, et al. The association of preoperative glycemic control, intraoperative insulin sensitivity, and outcomes after cardiac surgery. J Clin Endocrinol Metabol. 2010;95(9):4338–44.
Baban B, et al. Determination of insulin resistance in surgery: the choice of method is crucial. Clin Nutr. 2015;34(1):123–8.
Yuill KA, et al. The administration of an oral carbohydrate-containing fluid prior to major elective upper-gastrointestinal surgery preserves skeletal muscle mass postoperatively—a randomised clinical trial. Clin Nutr. 2005;24(1):32–7.
Henriksen MG, et al. Preoperative feeding might improve postoperative voluntary muscle function. Clin Nutr. 1999;18 Suppl 1:82.
Awad S, et al. A meta-analysis of randomised controlled trials on preoperative oral carbohydrate treatment in elective surgery. Clin Nutr. 2013;32(1):34–44.
Smith MD, et al. Preoperative carbohydrate treatment for enhancing recovery after surgery. Cochrane Database Syst. 2014;8, CD009161. doi:10.1002/14651858.CD009161.pub2.
Gustafsson UO, et al. Adherence to the enhanced recovery after surgery protocol and outcomes after colorectal cancer surgery. Arch Surg. 2011;146(5):571–7.
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Ljungqvist, O. (2015). Preoperative Fasting and Carbohydrate Treatment. In: Feldman, L., Delaney, C., Ljungqvist, O., Carli, F. (eds) The SAGES / ERAS® Society Manual of Enhanced Recovery Programs for Gastrointestinal Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-20364-5_4
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DOI: https://doi.org/10.1007/978-3-319-20364-5_4
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