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Progestin-Only Oral Contraceptives

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Part of the Current Clinical Practice book series (CCP)

Abstract

Progestin-only pills (POPs) are often referred to as “mini-pills” as they contain about 75 % of the progestin dose contained in combination oral contraceptives (COCs) and no estrogen. Their typical effectiveness has been shown to be slightly less than COCs; most likely due to a more limited duration of effect and inconsistent ovulation suppression. POPs are associated with more breakthrough bleeding than COCs but fewer serious adverse events. Although not as well studied, POPs are thought to have many of the same non-contraceptive health benefits as COCs.

Keywords

  • Progestin-only pills
  • POPs
  • Mini-pills
  • Ovulation suppression
  • Breakthrough bleeding
  • Non-contraceptive benefits

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References

  1. CDC. U.S. Medical eligibility criteria for contraceptive use. 2010. http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5904a1.htm?s_cid=rr5904a1_e. Accessed 31 May 2014.

  2. CDC. U.S. selected practice recommendations for contraceptive use. 2013. http://www.cdc.gov/mmwr/pdf/rr/rr62e0614.pdf. Accessed 31 May 2014.

  3. Edelman AB, Cherala G, Stanczyk FZ. Metabolism and pharmacokinetics of contraceptive steroids in obese women: a review. Contraception. 2010;82(4):314–23. doi:10.1016/j.contraception.2010.04.016.

    CAS  CrossRef  PubMed  Google Scholar 

  4. Medline Plus. Progestin-only oral contraception. 2010. www.nlm.nih.gov/medlineplus/druginfo/meds/a602008.html. Accessed 24 Apr 2014.

  5. Moghissi KS, Marks C. Effects of microdose norgestrel on endogenous gonadotropic and steroid hormones, cervical mucus properties, vaginal cytology, and endometrium. Fertil Steril. 1971;22(7):424–34.

    CAS  PubMed  Google Scholar 

  6. Rice CF, Killick SR, Dieben T, Coelingh Bennink H. A comparison of the inhibition of ovulation achieved by desogestrel 75 micrograms and levonorgestrel 30 micrograms daily. Hum Reprod. 1999;14(4):982–5.

    CAS  CrossRef  PubMed  Google Scholar 

  7. Speroff L, Darney P. A clinical guide for contraception. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2011.

    Google Scholar 

  8. Trussell J. Contraceptive failure in the United States. Contraception. 2011;83(5):397–404.

    PubMed Central  CrossRef  PubMed  Google Scholar 

  9. WHO. Selected practice recommendations for contraceptive use. WHO. 2004. http://whqlibdoc.who.int/publications/2004/9241562846.pdf. Accessed 31 May 2014.

  10. WHO. Medical eligibility criteria for contraceptive use. 2009. http://www.who.int/eproductivehealth/publications/family_planning/9789241563888/en/. Accessed 02 Jan 2010.

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Correspondence to Regina-Maria Renner MD, MPH, FRCSC, FACOG .

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Renner, RM., Edelman, A. (2016). Progestin-Only Oral Contraceptives. In: Shoupe, D., Mishell, Jr., D. (eds) The Handbook of Contraception. Current Clinical Practice. Humana Press, Cham. https://doi.org/10.1007/978-3-319-20185-6_5

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  • DOI: https://doi.org/10.1007/978-3-319-20185-6_5

  • Publisher Name: Humana Press, Cham

  • Print ISBN: 978-3-319-20184-9

  • Online ISBN: 978-3-319-20185-6

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