Skip to main content
SpringerLink
Log in

Breast Cancer Prevention in Summary

  • Chapter
  • First Online:
Breast Cancer Prevention and Treatment

  • 1487 Accesses

Abstract

In a consensus statement regarding breast cancer prevention, “preventive therapy” was the new term coined for “chemoprevention” [5]. The basics of this movement are founded on screening high-risk individuals and treating them with therapeutic measures in hopes of decreasing adverse outcomes. This has been compared to the successful demonstration in cardiology with screening lipid levels and treating with statins to prevent cardiovascular events [3].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Baigent C, Keech A, Kearney PM, Blackwell L, Buck G, Pollicino C, et al. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet. 2005;366:1267–78.

    Article  CAS  PubMed  Google Scholar 

  2. Radovich M, Clare SE, Atale R, Pardo I, Hancock BA, Solzak JP, et al. Characterizing the heterogeneity of triple-negative breast cancers using microdissected normal ductal epithelium and RNA-sequencing. Breast Cancer Res Treat. 2014;143(1):57–68.

    Article  CAS  PubMed  Google Scholar 

  3. Nelson HD, Tyne K, Naik A, Bougatsos C, Chan BK, Humphrey L. Screening for breast cancer: an update for the U.S. Preventive services task force. Ann Intern Med. 2009;151:727–37.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Autier P, Boniol M, Smans M, Sullivan R, Boyle P. Statistical analyses in Swedish randomized trials on mammography screening and in other randomized trials on cancer screening: a systematic review. J R Soc Med. 2015;108(11):440-50.

    Google Scholar 

  5. Harding C, Pompei F, Burmistrov D, Welch G, Abebe R, Wilson R. Breast cancer screening, incidence, and mortality across US counties. JAMA Intern Med. 2015;175(9):1483–9. Online publication 7/6/2015.

    Article  PubMed  Google Scholar 

  6. Miller AB, Wall C, Baines CJ, Sun P, To T, Narod SA. Twenty five year follow-up for breast cancer incidence and mortality of the Canadian National Breast Screening Study: randomised screening trial. BMJ. 2014;348:g366.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Koleva-Kolarova RG, Zhan Z, Greuter MJW, Feenstra TL, De Bock GH. Simulation models in population breast cancer screening: a systematic review. Breast. 2015;24:354–63.

    Article  PubMed  Google Scholar 

  8. McCormack VA, dos Santos Silva I. Breast density and parenchymal patterns as markers of breast cancer risk: a meta-analysis. Cancer Epidemiol Biomarkers Prev. 2006;15:1159–69.

    Article  PubMed  Google Scholar 

  9. Onega T, Beaber EF, Sprague BL, Barlow WE, Haas JS, Tosteson ANA, Schnall MD, Armstrong K, Schapira MM, Geller B, Weaver DL, Conant EF. Breast cancer screening in an era of personalized regimens. Cancer. 2014;120:2955–64.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Amir E, Freedman OC, Seruga B, Evans DG. Assessing women at high risk of breast cancer: a review of risk assessment models. J Natl Cancer Inst. 2010;102(10):680–91.

    Article  PubMed  Google Scholar 

  11. Goss PE, Ingle JN, Alés-Martínez JE, NCIC CTG MAP.3 Study investigators. Exemestane for breast-cancer prevention in postmenopausal women. N Engl J Med. 2011;364(25):2381–91.

    Article  CAS  PubMed  Google Scholar 

  12. Cuzick J, Sestak I, Forbes JF, Dowsett M, Knox J, Cawthorn S, Saunders C, Roche N, Mansel RE, von Minckwitz G, Bonanni B, Palva T, Howell A, IBIS-II investigators. Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial. Lancet. 2014;383:1041–8.

    Article  CAS  PubMed  Google Scholar 

  13. Cuzick J, DeCensi A, Arun B, Brown PH, Castiglione M, Dunn B, Forbes JF, Glaus A, Howell A, von Minckwitz G, Vogel V, Zwierzina H. Preventative therapy for breast cancer: a consensus statement. Lancet Oncol. 2011;12:496–503.

    Article  CAS  PubMed  Google Scholar 

  14. Maximov PY, Lee TM, Jordan VC. The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice. Curr Clin Pharmacol. 2013;8:135–55.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Tamoxifen drug summary. http://www.pdr.net/drug-summary/tamoxifen-citrate?druglabelid=664. Accessed 12 Aug 2015.

  16. Margolese RG, Cecchini RS, Julian TB, et al. Primary results, NRG Oncology/NSABP B-35: a clinical trial of anastrozole (A) versus tamoxifen (tam) in postmenopausal patients with DCIS undergoing lumpectomy plus radiotherapy. J Clin Oncol. 2015;33(suppl): abstr LBA500.

    Google Scholar 

  17. Pagani O, Regan MM, Walley BA, et al. Adjuvant exemestane with ovarian suppression in premenopausal breast cancer. N Engl J Med. 2014;371:107–18.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Catsburg C, Miller AB, Rohan TE. Adherence to cancer prevention guidelines and risk of breast cancer. Int J Cancer. 2014;135:2444–52.

    Article  CAS  PubMed  Google Scholar 

  19. Harvie M, Howell A, Evans DG. Can diet and lifestyle prevent breast cancer: what is the evidence? ASCO Educ Book. 2015:e66–73.

    Google Scholar 

  20. Friedenreich CM, Neilson HK, O’Reilly R, Duha A, Yasui Y, Morielli AR, Adams SC, Courneya KS. Effects of a high vs moderate volume of aerobic exercise on adiposity outcomes in postmenopausal women. JAMA Oncol. 2015;1(6):766–76. Online publication 7/16/2015.

    Article  PubMed  Google Scholar 

  21. Degnim AC, Visscher DW, Hoskin TL, Frost MH, Vierkant RA, Vachon CM, et al. Histologic findings in normal breast tissues: comparison to reduction mammoplasty and benign breast disease tissues. Breast Cancer Res Treat. 2012;133(1):169–77.

    Article  PubMed  Google Scholar 

  22. Sherman ME, Figurroa JD, Henry JE, Clare SE, Rufenbarger C, The SAM, Susan G. Komen for the Cure Tissue Bank at the IU Simon Cancer Center: a unique resource for defining the “molecular histology” of the breast. Cancer Prev Res. 2012;5:528–35.

    Article  Google Scholar 

  23. Stanton SE, Disis ML. Designing vaccines to prevent cancer recurrence or invasive disease. Immunotherapy. 2015;7(2):69–72. Editorial.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. IU Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN, USA

    Anna Maria Storniolo MD & Jill Kremer MD

Authors
  1. Anna Maria Storniolo MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jill Kremer MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Anna Maria Storniolo MD .

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Storniolo, A.M., Kremer, J. (2016). Breast Cancer Prevention in Summary. In: Breast Cancer Prevention and Treatment. Springer, Cham. https://doi.org/10.1007/978-3-319-19437-0_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-19437-0_8

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-19436-3

  • Online ISBN: 978-3-319-19437-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation