Pathology of Early Pregnancy Loss

  • T. Yee KhongEmail author


Early pregnancy losses can be divided into spontaneous abortion, ectopic pregnancies, and gestational trophoblastic disease. Much of the chapter is devoted to spontaneous abortion as it is the area that generally concerns perinatal pathologists more than the other two topics. Miscarriage is the most common complication of pregnancy. The term miscarriage is preferred to spontaneous abortion. Its definition, etiology, pathology, and pathogenesis are detailed. Differentiating between miscarriage and hydatidiform molar villous tissue is discussed, as are the practical considerations of differentiating between partial and complete moles and between molar triploidy and nonmolar triploidy.


Spontaneous abortion Miscarriage Etiology Parental factors Chromosomal abnormalities Congenital anatomical abnormalities Infection Maternal factors Occupational and environmental factors Pathology Placentation Angiogenesis Immunology Ectopic pregnancy Gestational trophoblastic disease Hydatidiform mole Triploidy 


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Copyright information

© Springer International Publishing 2015

Authors and Affiliations

  1. 1.Department of Pathology, Department of Obstetrics and GynaecologyUniversity of AdelaideNorth AdelaideAustralia
  2. 2.Department of HistopathologyWomen’s and Children’s HospitalNorth AdelaideAustralia

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