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Membrane Hydration: A Hint to a New Model for Biomembranes

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Membrane Hydration

Part of the book series: Subcellular Biochemistry ((SCBI,volume 71))

Abstract

The classical view of a biological membrane is based on the Singer-Nicholson mosaic fluid model in which the lipid bilayer is the structural backbone. Under this paradigm, many studies of biological processes such as, permeability, active transport, enzyme activity and adhesion and fusion processes have been rationalized considering the lipid membrane as a low dielectric slab of hydrocarbon chains with polar head groups exposed to water at each side in which oil/water partition prevails. In spite of several analyses and evidence available in relation to membrane hydration, water is not taken into account as a functional component. For this purpose, new insights in the water organization in restricted environments and the thermodynamical and mechanical properties emerging from them are specifically analysed and correlated.

This chapter summarizes the progress of the studies of water in membranes along the book in order to give a more realistic structural and dynamical picture accounting for the membrane functional properties.

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Authors and Affiliations

  1. Laboratorio de Biointerfases y Sistemas Biomimeticos, Centro de Investigacion y Transferencia de Santiago del Estero, Universidad Nacional de Santiago del Estero-Consejo Nacional de Investigaciones Científicas y Técnicas, 4200, Santiago del Estero, Argentina

    E. Anibal Disalvo

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  1. E. Anibal Disalvo
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Correspondence to E. Anibal Disalvo .

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  1. Laboratorio de Biointerfases y Sistemas Biomimeticos; Centro de Investigacion y Transferencia de Santiago del Estero, Universidad Nacional de Santiago del Estero-Consejo Nacional de Investigaciones Científicas y Técnicas, El Zanjón, Santiago del Estero, Argentina

    E. Anibal Disalvo

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Disalvo, E.A. (2015). Membrane Hydration: A Hint to a New Model for Biomembranes. In: Disalvo, E. (eds) Membrane Hydration. Subcellular Biochemistry, vol 71. Springer, Cham. https://doi.org/10.1007/978-3-319-19060-0_1

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