Mucoid Discharge Associated with Prosthetic Eye Wear

  • Keith R. Pine
  • Brian H. Sloan
  • Robert J. Jacobs


Excessive mucoid discharge associated with prosthetic eye wear is a common occurrence that, according to a New Zealand survey of 431 prosthetic eye wearers, affects 93 % of wearers – 60 % of them on a daily basis [1]. This is a serious problem for those involved in the care of anophthalmic patients because the success of prosthetic restoration depends upon both the cosmesis and the convenience of wearing the prosthesis [2]. Mucoid discharge has been found to be the second highest concern for experienced prosthetic eye wearers after the health of the remaining eye [1] and clearly impacts negatively on the quality of life of anophthalmic patients who suffer it.


Contact Lens Meibomian Gland Eyelid Margin Keratoconjunctivitis Sicca Meibomian Gland Dysfunction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Pine KR, Sloan B, Stewart J, Jacobs RJ. Concerns of anophthalmic patients wearing artificial eyes. Clin Experiment Ophthalmol. 2011;39(1):47–52.PubMedGoogle Scholar
  2. 2.
    Clarke A. Psychosocial aspects of facial disfigurement: problems, management, and the role of a lay-led organization. Psychol Health Med. 1999;4:127–42.CrossRefGoogle Scholar
  3. 3.
    Benitez-del-Castillo JM. How to promote and preserve eyelid health. Clin Ophthalmol. 2012;6:1689–98.PubMedCentralPubMedCrossRefGoogle Scholar
  4. 4.
    Arita R, Itoh K, Inoue K, et al. Contact lens wear is associated with decrease of meibomian glands. Ophthalmology. 2009;116:379–84.PubMedCrossRefGoogle Scholar
  5. 5.
    Jang SY, Lee SY, Yoon JS. Meibomian gland dysfunction in long standing prosthetic eye wearers. Br J Ophthalmol. 2013;97(4):398–402.PubMedCrossRefGoogle Scholar
  6. 6.
    Kim SE, Yoon JS, Lee SY, Kim SE, Yoon JS, Lee SY. Tear measurement in prosthetic eye users with Fourier-domain optical coherence tomography. Am J Ophthalmol. 2011;149(4):602–7.e1.CrossRefGoogle Scholar
  7. 7.
    Macsai MS. The role of Omega-3 dietary supplementation in blepharitis and meibomian gland dysfunction (MGD). Trans Am Ophthalmol Soc. 2008;106:336–56.PubMedCentralPubMedGoogle Scholar
  8. 8.
    Vardizer Y, Lang Y, Mourits MP, et al. Favorable effects of lacrimal plugs in patients with an anophthalmic socket. Orbit. 2007;26:263–6.PubMedCrossRefGoogle Scholar
  9. 9.
    Dykewicz MS, Hamilos DL. Rhinitis and sinusitis. J Allergy Clin Immunol. 2010;125:S103–15.PubMedCrossRefGoogle Scholar
  10. 10.
    Anderson JN, Storer R. Immediate and replacement dentures. Oxford: Blackwell Scientific Publishing; 1966.Google Scholar
  11. 11.
    Patel V, Allen D, Morley AM, et al. Features and management of an acute allergic response to acrylic ocular prostheses. Orbit. 2009;28:339–41.PubMedCrossRefGoogle Scholar
  12. 12.
    Smith DC, Bains MED. Residual methyl methacrylate in the denture base and its relation to denture sore mouth. Br Dent J. 1955;98:55–8.Google Scholar
  13. 13.
    Pine KR, Sloan B, Jacobs RJ. Deposit buildup on prosthetic eye material (in vitro) and its effect on surface wettability. Clin Ophthalmol. 2013;7:313–9.PubMedCentralPubMedCrossRefGoogle Scholar
  14. 14.
    Jones CA, Collin JR. A classification and review the causes of discharging sockets. Trans Ophthalmol Soc UK. 1983;103(3):351–3.PubMedGoogle Scholar
  15. 15.
    Pine K, Sloan B, Stewart J, Jacobs RJ. A survey of prosthetic eye wearers to investigate mucoid discharge. Clin Ophthalmol. 2012;6:707–13.PubMedCentralPubMedGoogle Scholar
  16. 16.
    Vasquez RJ, Linberg JV. The anophthalmic socket and the prosthetic eye. A clinical and bacteriologic study. Ophthal Plast Reconstr Surg. 1989;5(4):277–80.PubMedCrossRefGoogle Scholar
  17. 17.
    Pine KR, Sloan B, Jacobs R. Deposit build-up on prosthetic eyes and the implications for conjunctival inflammation and mucoid discharge. Clin Ophthalmol. 2012;6:1–8.Google Scholar
  18. 18.
    Allen L, Kolder HE, Bulgarelli EM, Bulgarelli DM. Prosthetic eyes and tear measurements. Ophthalmology. 1980;87(2):155–7.PubMedCrossRefGoogle Scholar
  19. 19.
    Fett DR, Scott R, Putterman AM. Evaluation of lubricants for the prosthetic a. eye wearer. Ophthal Plast Reconstr Surg. 1986;2(1):29–31.PubMedCrossRefGoogle Scholar
  20. 20.
    Spring TF. Reaction to hydrophilic lenses. Med J Aust. 1974;1(12):449–50.PubMedGoogle Scholar
  21. 21.
    Donshik PC. Extended wear contact lenses. Ophthalmol Clin North Am. 2003;16(3):305–9.PubMedCrossRefGoogle Scholar
  22. 22.
    Donshik PC. Giant papillary conjunctivitis. Trans Am Ophthalmol Soc. 1994;92:687–744.PubMedCentralPubMedGoogle Scholar
  23. 23.
    Gellatly KW, Brennan NA, Efron N. Visual decrement with deposit accumulation on HEMA contact lenses. Am J Optom Physiol Opt. 1988;65(12):937–41.PubMedCrossRefGoogle Scholar
  24. 24.
    Grant T, Holden BA, Rechberger J. Contact lens related papillary conjunctivitis (CLPC). Influence of protein accumulation and replacement frequency. Invest Ophthalmol Vision Sci. 1989;30(3 Suppl):166.Google Scholar
  25. 25.
    Lever OW, Groemminger SF, Allen ME. Evaluation of the relationship between total lens protein deposition and patient-rated comfort of hydrophilic (soft) contact lenses. ICLC. 1995;22(1):5–13.Google Scholar
  26. 26.
    Subbaraman LN, Glasier M, Varikooty J, Srinivasan S, Jones L. Protein deposition and clinical symptoms in daily wear of etafilcon lenses. Optom Vis Sci. 2012;89(10):1450–9.PubMedCrossRefGoogle Scholar
  27. 27.
    Pine KR, Sloan B, Jacobs RJ. A proposed model of the response of the anophthalmic socket to prosthetic eye wear and its application to the management of mucoid discharge. Med Hypotheses. 2013;81(2):300–5.PubMedCrossRefGoogle Scholar
  28. 28.
    Keith DJ, Christensen MT, Barry JR, Stein JM. Determination of the lysozyme deposit curve in soft contact lenses. Eye Contact Lens. 2003;29(2):79–82.PubMedCrossRefGoogle Scholar
  29. 29.
    LeGrand JA. Chronic exudate: an unnecessary evil. J Ophthalmic Prosthet. 1999;4(1):33–40.Google Scholar
  30. 30.
    Ophthalmology Unit, University of Malaysia Sarawak. Post enucleation socket syndrome. Accessed 27 Jun 2015.

Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Keith R. Pine
    • 1
  • Brian H. Sloan
    • 2
  • Robert J. Jacobs
    • 1
  1. 1.School of Optometry and Vision ScienceThe University of AucklandAucklandNew Zealand
  2. 2.New Zealand National Eye CentreThe University of AucklandAucklandNew Zealand

Personalised recommendations