Abstract
Scanning laser polarimetry (SLP), also known as GDx, is an imaging technology based on the retardation of light that has double-passed the birefringent fibers of the retinal nerve fiber layer (RNFL). Light retardation correlates well with the RNFL thickness. This device compensates the birefringent effect of the anterior segment (cornea and lens) individually for every eye to improve the diagnostic accuracy for glaucoma. The last version of this instrument is the GDx with enhanced corneal compensation (ECC), which has shown a better accuracy in atypical retardation patterns.
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References
Weinreb RN, Dreher AW, Coleman A, Quigley HA, Shaw B, Reiter K (1990) Histopathologic validation of Fourier-ellipsometry measurements of retinal nerve fiber layer thickness. Arch Ophthalmol 108:557–560
Morgan JE, Waldock A, Jeffery G, Cowey A (1998) Retinal nerve fiber layer polarimetry: histological and clinical comparison. Br J Ophthalmol 82:684–690
Reus NJ, Lemij HG (2004) Diagnostic accuracy of the GDx VCC for glaucoma. Ophthalmology 111:1860–1865
Medeiros F, Zangwill LM, Bowd C, Mohammadi K, Weinreb RN (2004) Comparison of scanning laser polarimetry using variable corneal polarization compensation and retinal nerve fiber layer photography for detection of glaucoma. Am J Ophthalmol 138:592–601
Garway-Heath DF, Greaney MJ, Caprioli J (2002) Correction for the erroneous compensation of anterior segment birenfringence with the scanning laser polarimeter for glaucoma diagnosis. Invest Ophthalmol Vis Sci 43(5):1465–1474
Zhou Q, Weinreb RN (2002) Individualized compensation of anterior segment birefringence during scanning laser polarimetry. Invest Ophthalmol Vis Sci 43:2221–2228
Greenfield DS, Knighton RW, Feuer W, Schiffman J, Zangwill L, Weinreb RN (2002) Correction for corneal polarization axis improves the discriminating power of scanning laser polarimetry. Ophthalmology 108:1065–1069
Reus NJ, Colen TP, Lemij HG (2003) Visualization of localized retinal nerve fiber layer defects with the GDX with individualized and with fixed compensation of anterior segment birefringence. Ophthalmology 110:1512–1516
Ferreras A, Pablo LE, PajarÃn AB, GarcÃa-Feijoo J, Honrubia FM (2009) Scanning laser polarimetry: logistic regression analysis for perimetric glaucoma diagnosis. Eye 23(3):593–600
Tóth M, Holló G (2005) Enhanced corneal compensation for scanning laser polarimetry on eyes with atypical polarisation pattern. Br J Ophthalmol 89(9):1139–1142
Sehi M, Guaqueta DC, Greenfield DS (2006) An enhancement module to improve the atypical birefringence pattern using scanning laser polarimetry with variable corneal compensation. Br J Ophthalmol 90(6):749–753
Reus NJ, Zhou Q, Lemij HG (2006) Enhanced imaging algorithm for scanning laser polarimetry with variable corneal compensation. Invest Ophthalmol Vis Sci 47(9):3870–3877
Bowd C, Tavares IM, Medeiros FA, Zangwill LM, Sample PA, Weinreb RN (2007) Retinal nerve fiber layer thickness and visual sensitivity using scanning laser polarimetry with variable and enhanced corneal compensation. Ophthalmology 114(7):1259–1265
Sehi M, Guaqueta DC, Feuer WJ, Greenfield DS, Advanced Imaging in Glaucoma Study Group (2007) Scanning laser polarimetry with variable and enhanced corneal compensation in normal and glaucomatous eyes. Am J Ophthalmol 143(2):272–279
Medeiros FA, Bowd C, Zangwill LM, Patel C, Weinreb RN (2007) Detection of glaucoma using scanning laser polarimetry with enhanced corneal compensation. Invest Ophthalmol Vis Sci 48(7):3146–3153
Mai TA, Reus NJ, Lemij HG (2007) Diagnostic accuracy of scanning laser polarimetry with enhanced versus variable corneal compensation. Ophthalmology 114(11):1988–1993
Grewal DS, Sehi M, Greenfield DS (2011) Detecting glaucomatous progression using GDx with variable and enhanced corneal compensation using Guided Progression Analysis. Br J Ophthalmol 95(4):502–508
Rao HL, Yadav RK, Begum VU, Addepalli UK, Senthil S, Choudhari NS, Garudadri CS (2015) Atypical birefringence pattern and the diagnostic ability of scanning laser polarimetry with enhanced corneal compensation in glaucoma. Acta Ophthalmol 93(2):e105–e110
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Schlottmann, P.G., Calvo, P. (2016). Detection of Glaucoma Using Scanning Laser Polarimetry. In: Ferreras, A. (eds) Glaucoma Imaging. Springer, Cham. https://doi.org/10.1007/978-3-319-18959-8_8
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DOI: https://doi.org/10.1007/978-3-319-18959-8_8
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-18958-1
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